{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T12:03:32Z","timestamp":1791029012300,"version":"4.1.0"},"reference-count":14,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1993,1,1]],"date-time":"1993-01-01T00:00:00Z","timestamp":725846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[1993,1]]},"abstract":"<jats:p>\n                    A study to evaluate the effects of dietary fumonisin B, was conducted using 6 ponies (4 test and 2 control). A ration naturally contaminated with fumonisin B, was fed in 3 phases: 1) 44 ppm fumonisin B\n                    <jats:sub>1<\/jats:sub>\n                    , 2) less than 1 ppm fumonisin B\n                    <jats:sub>1<\/jats:sub>\n                    , and 3) 88 ppm fumonisin B,. All ponies were monitored daily, weighed weekly, and limit fed at a rate of 0.8% body weight plus hay. Feed intake was measured daily, and a serum chemistry panel was completed once or twice weekly. Four to 7 days after initiation of the trial (Phase 1), all 4 test ponies had decreased feed consumption, and selected serum chemistry parameters were markedly elevated. On day 9, 1 pony died acutely with mild encephalopathy and hepatic necrosis. Another pony, euthanized on day 45, also had mild encephalopathy and hepatic necrosis. The remaining 2 test ponies continued the 44 ppm fumonisin B, diet for 98 days. Phase 2 consisted of a diet with &lt; 1 ppm fumonisin B, for 120 days. During this phase, the serum chemistry values of the 2 ponies returned to normal. Following Phase 2, the 2 ponies were fed a diet containing 88 ppm fumonisin B\n                    <jats:sub>1<\/jats:sub>\n                    . After 75 days, 1 animal died of equine leukoencephalomalacia with mild hepatic necrosis. On day 78, the remaining pony was euthanized after showing distress; it also had leukoencephalomalacia and hepatic lesions.\n                  <\/jats:p>","DOI":"10.1177\/104063879300500115","type":"journal-article","created":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T16:10:00Z","timestamp":1305216600000},"page":"69-74","source":"Crossref","is-referenced-by-count":86,"title":["Experimental Equine Leukoencephalomalacia, Toxic Hepatosis, and Encephalopathy Caused by Corn Naturally Contaminated with Fumonisins"],"prefix":"10.1177","volume":"5","author":[{"given":"P. F.","family":"Ross","sequence":"first","affiliation":[{"name":"US Department of Agriculture, Animal and Plant Health Inspection Service, Science and Technology, National Veterinary Services Laboratories, Ames, IA 50010"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. E.","family":"Ledet","sequence":"additional","affiliation":[{"name":"Iowa State University, Ames, IA 50011"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. L.","family":"Owens","sequence":"additional","affiliation":[{"name":"US Department of Agriculture, Animal and Plant Health Inspection Service, Science and Technology, National Veterinary Services Laboratories, Ames, IA 50010"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. G.","family":"Rice","sequence":"additional","affiliation":[{"name":"US Department of Agriculture, Animal and Plant Health Inspection Service, Science and Technology, National Veterinary Services Laboratories, Ames, IA 50010"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. A.","family":"Nelson","sequence":"additional","affiliation":[{"name":"US Department of Agriculture, Animal and Plant Health Inspection Service, Science and Technology, National Veterinary Services Laboratories, Ames, IA 50010"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. D.","family":"Osweiler","sequence":"additional","affiliation":[{"name":"Iowa State University, Ames, IA 50011"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. M.","family":"Wilson","sequence":"additional","affiliation":[{"name":"US Department of Agriculture, Animal and Plant Health Inspection Service, Science and Technology, National Veterinary Services Laboratories, Ames, IA 50010"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1993,1,1]]},"reference":[{"key":"bibr1-104063879300500115","first-page":"636","volume":"35","author":"Biester HE","year":"1940","journal-title":"Vet Med"},{"key":"bibr2-104063879300500115","first-page":"34","volume":"29","author":"Brownie CF","year":"1987","journal-title":"Vet Hum Toxicol"},{"key":"bibr3-104063879300500115","first-page":"239","volume":"22","author":"Buck WB","year":"1979","journal-title":"Proc Annu Meet Am Assoc Lab Diagn"},{"key":"bibr4-104063879300500115","first-page":"75","volume":"33","author":"Haliburton JC","year":"1986","journal-title":"Curr Top Vet Med Anim Sci"},{"key":"bibr5-104063879300500115","first-page":"205","volume":"39","author":"Kellerman TS","year":"1972","journal-title":"Onderstepoort J Vet Res"},{"key":"bibr6-104063879300500115","first-page":"269","volume":"57","author":"Kellerman TS","year":"1990","journal-title":"Onderstepoort J Vet Res"},{"key":"bibr7-104063879300500115","first-page":"129","volume":"48","author":"Kriek NPJ","year":"1981","journal-title":"Onderstepoort J Vet Res"},{"key":"bibr8-104063879300500115","first-page":"197","volume":"55","author":"Marasas WFO","year":"1988","journal-title":"Onderstepoort J Vet Res"},{"key":"bibr9-104063879300500115","first-page":"113","volume":"43","author":"Marasas WFO","year":"1976","journal-title":"Onderstepoort J Vet Res"},{"key":"bibr10-104063879300500115","first-page":"646","volume":"11","author":"McCue PM","year":"1989","journal-title":"Compendium"},{"key":"bibr11-104063879300500115","doi-asserted-by":"publisher","DOI":"10.1007\/BF00437200"},{"key":"bibr12-104063879300500115","doi-asserted-by":"publisher","DOI":"10.1021\/jf00001a021"},{"key":"bibr13-104063879300500115","doi-asserted-by":"publisher","DOI":"10.1136\/vr.88.19.484"},{"key":"bibr14-104063879300500115","doi-asserted-by":"publisher","DOI":"10.1177\/104063879000200311"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063879300500115","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063879300500115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:32:46Z","timestamp":1777681966000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/104063879300500115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1993,1]]}},"alternative-id":["10.1177\/104063879300500115"],"URL":"https:\/\/doi.org\/10.1177\/104063879300500115","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,1]]}}}