{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:44:07Z","timestamp":1777931047483,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1993,4,1]],"date-time":"1993-04-01T00:00:00Z","timestamp":733622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[1993,4]]},"abstract":"<jats:p>A severe bleeding disorder in Simmental cattle has been described in widespread locations in the USA and Canada. The clinical findings are consistent with a hemophilia-like disease or, more precisely, a hereditary hemorrhagic diathesis and include spontaneous epistaxis, hematuria, and excessive bleeding associated with trauma or standard management procedures such as tattooing, ear tagging, and castration. A preliminary investigation of this defect showed that blood-platelet numbers and coagulation profiles of affected cattle were normal. Affected animals have a marked dysfunction of platelets (thrombopathy), termed Simmental hereditary thrombopathy. The defect is very similar or identical to that described in the same breed by 2 other laboratories.<\/jats:p>","DOI":"10.1177\/104063879300500211","type":"journal-article","created":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T16:10:00Z","timestamp":1305216600000},"page":"202-207","source":"Crossref","is-referenced-by-count":14,"title":["Hemorrhagic Diathesis Associated with a Hereditary Platelet Disorder in Simmental Cattle"],"prefix":"10.1177","volume":"5","author":[{"given":"Barbara A.","family":"Steficek","sequence":"first","affiliation":[{"name":"Department of Pathology and the Animal Health Diagnostic Laboratory, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer S.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Pathology and the Animal Health Diagnostic Laboratory, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.","family":"Baker","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas G.","family":"Bell","sequence":"additional","affiliation":[{"name":"Department of Pathology and the Animal Health Diagnostic Laboratory, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1993,4,1]]},"reference":[{"key":"bibr1-104063879300500211","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V48.2.175.175"},{"key":"bibr2-104063879300500211","first-page":"67","volume":"92","author":"Bondy GS","year":"1989","journal-title":"Comp Biochem Physiol"},{"key":"bibr3-104063879300500211","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.4.5.2407587"},{"key":"bibr4-104063879300500211","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)69080-5"},{"key":"bibr5-104063879300500211","doi-asserted-by":"crossref","first-page":"919","DOI":"10.2460\/ajvr.1989.50.06.919","volume":"50","author":"Gentry PA","year":"1989","journal-title":"Am J Vet Res"},{"key":"bibr6-104063879300500211","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4889(89)90077-3"},{"key":"bibr7-104063879300500211","first-page":"446","volume":"9","author":"Kociba GJ","year":"1980","journal-title":"Vet Clin Pathol"},{"key":"bibr8-104063879300500211","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)34378-3"},{"key":"bibr9-104063879300500211","volume-title":"Second registry of animal models of thrombosis and hemorrhagic diseases, P.R17","author":"Dodds WJ","year":"1981"},{"key":"bibr10-104063879300500211","doi-asserted-by":"publisher","DOI":"10.3109\/10520297709116767"},{"key":"bibr11-104063879300500211","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)49264-2"},{"key":"bibr12-104063879300500211","first-page":"101","volume":"31","author":"Searcy GP","year":"1990","journal-title":"Can Vet J"},{"key":"bibr13-104063879300500211","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1989.69.1.58"},{"key":"bibr14-104063879300500211","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(93)90216-B"},{"key":"bibr15-104063879300500211","first-page":"523","volume-title":"Platelet membrane receptors: Molecular biology, immunology, biochemistry and pathology","author":"Sweatt JD","year":"1988"},{"key":"bibr16-104063879300500211","first-page":"135","volume":"77","author":"White JG","year":"1974","journal-title":"Am J Pathol"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063879300500211","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063879300500211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:32:59Z","timestamp":1777681979000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/104063879300500211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,4]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1993,4]]}},"alternative-id":["10.1177\/104063879300500211"],"URL":"https:\/\/doi.org\/10.1177\/104063879300500211","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,4]]}}}