{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T22:54:38Z","timestamp":1788389678338,"version":"build-2803163510"},"reference-count":55,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Pediatr Oncol Nurs"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:p>The purpose of this study was to compare anxiety, depression, and stress between mothers of children during maintenance treatment for acute lymphoblastic leukemia (ALL) and matched controls. Twenty-six mothers were recruited from the hematology unit at a children\u2019s hospital, and 26 mothers were recruited from the community. Participants were matched to their child\u2019s age and gender. Mothers completed the Hospital Anxiety and Depression Scale, the Perceived Stress Sale, and collected salivary cortisol 4 times a day for 3 consecutive days. Compared with mothers of healthy children, anxiety scores did not differ ( P = .10), but depression scores were higher ( P = .003) in mothers of children with ALL. More mothers in the ALL group scored above the cutoff of 7 indicating clinical anxiety (46%) and depressive symptoms (27%). A trend toward increased stress was found in mothers in the ALL group. No difference was found in overall daily cortisol (area under the curve), daily decrease in cortisol (slope), and cortisol awakening response. Mothers of children with ALL experienced emotional symptoms many months after the initial diagnosis.<\/jats:p>","DOI":"10.1177\/1043454213520346","type":"journal-article","created":{"date-parts":[[2014,3,7]],"date-time":"2014-03-07T18:16:52Z","timestamp":1394216212000},"page":"104-113","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":31,"title":["Anxiety, Depression, Stress, and Cortisol Levels in Mothers of Children Undergoing Maintenance Therapy for Childhood Acute Lymphoblastic Leukemia"],"prefix":"10.1177","volume":"31","author":[{"given":"Madalynn","family":"Neu","sequence":"first","affiliation":[{"name":"University of Colorado Anschutz Medical Campus, Aurora CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellyn","family":"Matthews","sequence":"additional","affiliation":[{"name":"University of Colorado Anschutz Medical Campus, Aurora CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy A.","family":"King","sequence":"additional","affiliation":[{"name":"University of Colorado, Denver, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul F.","family":"Cook","sequence":"additional","affiliation":[{"name":"University of Colorado Anschutz Medical Campus, Aurora CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark L.","family":"Laudenslager","sequence":"additional","affiliation":[{"name":"University of Colorado Anschutz Medical Campus, Aurora CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,3,7]]},"reference":[{"key":"bibr1-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.165.5.669"},{"key":"bibr2-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-013-1098-6"},{"key":"bibr3-1043454213520346","doi-asserted-by":"publisher","DOI":"10.3399\/bjgp08X263794"},{"key":"bibr4-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0042324"},{"key":"bibr5-1043454213520346","first-page":"31","volume-title":"The social psychology of health: Claremont Symposium on Applied Social Psychology","author":"Cohen S.","year":"1988"},{"key":"bibr6-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1037\/1082-989X.6.4.330"},{"key":"bibr7-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandc.2012.01.002"},{"key":"bibr8-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1007\/s10880-011-9229-4"},{"key":"bibr9-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsmo13"},{"key":"bibr10-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2008.03.014"},{"key":"bibr11-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen2005.04.006"},{"key":"bibr12-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4530(01)00081-6"},{"key":"bibr13-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1521\/psyc.2006.69.3.191"},{"key":"bibr14-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-013-0325-5"},{"key":"bibr15-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4682-4-8"},{"key":"bibr16-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(05)70208-5"},{"key":"bibr17-1043454213520346","first-page":"935","volume-title":"Nursing care of children and adolescents with cancer and blood disorders","author":"Hobbie W. L.","year":"2011","edition":"4"},{"key":"bibr18-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e31818a9553"},{"key":"bibr19-1043454213520346","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2013.00314"},{"key":"bibr20-1043454213520346","doi-asserted-by":"publisher","DOI":"10.4291\/wigp.v4.i4.108"},{"key":"bibr21-1043454213520346","first-page":"222","volume":"22","author":"Imam M. A.","year":"2013","journal-title":"Mymensingh Medicine Journal"},{"key":"bibr22-1043454213520346","first-page":"6","volume":"14","author":"Iqbal A.","year":"2002","journal-title":"Journal of Ayub Medical College, Abbottabad"},{"key":"bibr23-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1080\/16506073.2010.538432"},{"key":"bibr24-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsh02"},{"key":"bibr25-1043454213520346","doi-asserted-by":"publisher","DOI":"10.100\/jamapsychiatry.2013.2798"},{"key":"bibr26-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4682-10-65"},{"key":"bibr27-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j\/psyneuen.2013.01.006"},{"key":"bibr28-1043454213520346","doi-asserted-by":"publisher","DOI":"10.3109\/10253890.2013.817552"},{"key":"bibr29-1043454213520346","volume-title":"Stress, appraisal and coping","author":"Lazarus R. S.","year":"1984"},{"key":"bibr30-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579401003133"},{"key":"bibr31-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1188\/02.ONF.988-996"},{"key":"bibr32-1043454213520346","doi-asserted-by":"publisher","DOI":"10.3109\/01460860903486572"},{"key":"bibr33-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.133.1.25"},{"key":"bibr34-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.158.2.255"},{"key":"bibr35-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2006.04\/003"},{"key":"bibr36-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2004.10.005"},{"key":"bibr37-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1159\/000216184"},{"key":"bibr38-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2007.11.002"},{"key":"bibr39-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4530(02)00108-7"},{"key":"bibr40-1043454213520346","volume-title":"Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995","author":"Ries L. A. G.","year":"1999"},{"key":"bibr41-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2003.11.018"},{"key":"bibr42-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.73.2.272"},{"key":"bibr43-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000116715.78238.56"},{"key":"bibr44-1043454213520346","doi-asserted-by":"crossref","unstructured":"Snaith R. P. (2003). The Hospital Anxiety and Depression Scale. Health and Quality of Life Outcomes, 1(29). Retrieved from http:\/\/www.hqlo.com\/content\/1\/1\/29","DOI":"10.1186\/1477-7525-1-29"},{"key":"bibr45-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(00)00204-3"},{"key":"bibr46-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2008.10.023"},{"key":"bibr47-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2012.02.002"},{"key":"bibr48-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsp139"},{"key":"bibr49-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2003.08.005"},{"key":"bibr50-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2006.05.012"},{"key":"bibr51-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(02)00429-4"},{"key":"bibr52-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.56.10.897"},{"key":"bibr53-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2005.06.010"},{"key":"bibr54-1043454213520346","first-page":"B17","author":"Zavagli V.","year":"2012","journal-title":"Giornale Italiano di Medicina del Lavoro ed Ergonomia, 34"},{"key":"bibr55-1043454213520346","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"}],"container-title":["Journal of Pediatric Oncology Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1043454213520346","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1043454213520346","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1043454213520346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:30:06Z","timestamp":1777509006000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1043454213520346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":55,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1177\/1043454213520346"],"URL":"https:\/\/doi.org\/10.1177\/1043454213520346","relation":{},"ISSN":["1043-4542","1532-8457"],"issn-type":[{"value":"1043-4542","type":"print"},{"value":"1532-8457","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3]]}}}