{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T05:39:09Z","timestamp":1792388349483,"version":"4.4.0"},"reference-count":78,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T00:00:00Z","timestamp":1787443200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T00:00:00Z","timestamp":1787443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Cincinnati Children\u2019s Hospital Medical Center (CCHMC) Place Outcomes Research Award"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Child and Adolescent Psychopharmacology"],"published-print":{"date-parts":[[2026,12,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>\n                      Autistic youth often face difficulties with emotion dysregulation (ED) and associated challenging behaviors. The\n                      <jats:italic toggle=\"yes\">Regulating Together<\/jats:italic>\n                      (RT) group therapy was developed to treat ED in autistic youth ages 8\u201318 years and has been shown to be feasible, acceptable, and efficacious at reducing ED. Results from other clinical trials suggest the efficacy of behavioral therapies may vary based on family- or neighborhood-level social determinants of health (SDOH: \u201cthe conditions in the environments where people are born, live, learn, work, play, worship, and age that affect a wide range of health, functioning, and quality-of-life outcomes and risks\u201d; U.S. Department of Health and Human Services). The extent to which these factors modify treatment response for RT is not known. This knowledge may help identify characteristics of treatment responders, inform implementation strategies to maximize real-world effectiveness, and guide decisions around treatment assignment and dosing.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      This is an exploratory, secondary analysis of our previously reported in-person (\n                      <jats:italic toggle=\"yes\">N<\/jats:italic>\n                      = 37) and telehealth (\n                      <jats:italic toggle=\"yes\">N<\/jats:italic>\n                      = 26) nonrandomized trials of RT. Participants included 63 autistic youth (79.3% male; mean age = 12.8 years, SD = 2.9, range = 8\u201318) and caregivers. ED and related constructs (e.g., cognitive inflexibility) were assessed at baseline, post-treatment, and 5- and 10-week follow-up visits. Neighborhood-level SDOH were indexed using the Child Opportunity Index based on participants\u2019 home addresses. Linear mixed-effects models tested whether neighborhood opportunity moderated treatment response.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Neighborhood opportunity was unrelated to baseline clinical characteristics. However, neighborhood opportunity moderated treatment outcomes: reductions in irritability and emotional reactivity were greatest among families in neighborhoods with fewer opportunities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Our finding of an amplified treatment response among families living in neighborhoods with fewer resources aligns with results from clinical trials for disruptive behaviors and internalizing disorders in typically developing youth. Possible explanations for this include families\u2019 limited prior access to behavioral health services, secondary reductions in caregiver stress, or high satisfaction with RT. These results challenge assumptions about diminished efficacy in low-resource settings and underscore the importance of considering contextual factors in future trials to enhance real-world impact.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10445463261477348","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T05:26:17Z","timestamp":1787549177000},"page":"649-660","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Families\u2019 Neighborhood Resources Predict Treatment Response for Regulating Together, a Group Therapy for Emotion Dysregulation in Autistic Youth"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5281-3749","authenticated-orcid":false,"given":"Walker S.","family":"McKinney","sequence":"first","affiliation":[{"name":"Division of Developmental and Behavioral Health, Children\u2019s Mercy Kansas City, Kansas City, Missouri, USA."},{"name":"Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Missouri, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren M.","family":"Schmitt","sequence":"additional","affiliation":[{"name":"Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."},{"name":"Phelan-McDermid Syndrome Foundation, Venice, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer R.","family":"Ruberg","sequence":"additional","affiliation":[{"name":"Division of Child and Adolescent Psychiatry, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marika","family":"Coffman","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Duke Center for Autism and Brain Development, Duke University, Durham, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debra","family":"Reisinger","sequence":"additional","affiliation":[{"name":"Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca C.","family":"Shaffer","sequence":"additional","affiliation":[{"name":"Department of Behavioral Medicine and Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,23]]},"reference":[{"key":"e_1_3_4_2_1","volume-title":"Parenting Stress Index","author":"Abidin RR","year":"2012","unstructured":"Abidin RR. Parenting Stress Index: Fourth Edition. Lutz, FL: PAR, Inc.; 2012."},{"key":"e_1_3_4_3_1","volume-title":"Aberrant Behavior Checklist","author":"Aman MG","year":"2017","unstructured":"Aman MG, , Singh NN. Aberrant Behavior Checklist, Second Edition. East Aurora: Slosson Educational Publications, Inc.; 2017."},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2025.116484"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.1506.04967"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v067.i01"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.21105\/joss.02815"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/1077558705285298"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/aur.3199"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/15374416.2021.1941058"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2024.1401148"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10567-016-0208-z"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0035458"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-3737.2010.00725.x"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-020-04370-1"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/aur.2450"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2018.03.044"},{"key":"e_1_3_4_18_1","unstructured":"diversitydatakids.org. Child Opportunity Index 3.0 database 2010 census tracts 2024. Available from: https:\/\/data.diversitydatakids.org\/dataset\/coi30-2010-tracts-child-opportunity-index-3-0-database\u20132010-census-tracts?_external=True [Last accessed Nov15 2024]."},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2010.07.005"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-8624.2004.00674.x"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-025-07056-8"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1037\/ccp0000784"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.13962"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-023-10175-6"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40894-023-00228-6"},{"key":"e_1_3_4_26_1","volume-title":"Behavior Rating Inventory of Executive Function\u00ae","author":"Gioia GA","year":"2015","unstructured":"Gioia GA, , Isquith PK, , Guy SC, et al. Behavior Rating Inventory of Executive Function\u00ae, Second Edition (BRIEF\u00ae2). Lutz, FL: PAR Inc.; 2015."},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.7812\/TPP\/18-078"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1300\/J079v26n04_02"},{"key":"e_1_3_4_29_1","doi-asserted-by":"crossref","unstructured":"Jaeger B. r2glmm: Computes R Squared for Mixed (Multilevel) Models 2017. Available from: https:\/\/cran.r-project.org\/web\/packages\/r2glmm\/index.html","DOI":"10.32614\/CRAN.package.r2glmm"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2022.09.307"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-013-1970-0"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2026.105317"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.9.1548"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.5127\/pr.034613"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-8624.2007.01117.x"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1177\/1362361321990931"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpr.1576"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2012.14.3\/mlerner"},{"key":"e_1_3_4_39_1","volume-title":"Autism Diagnostic Observation Schedule","author":"Lord C","year":"2012","unstructured":"Lord C, , Rutter M, , DiLavore PC, et al. Autism Diagnostic Observation Schedule, Second Edition (ADOS-2). Torrance, CA: Western Psychological Services; 2012."},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1300\/J019v26n02_03"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1080\/19315864.2017.1338804"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-016-2907-1"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/aur.1947"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1186\/1744-859X-11-16"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2025.1636987"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40359-025-02737-6"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph21121572"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthplace.2021.102728"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579420001273"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.20220558"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10578-005-0003-4"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2041-210x.2012.00261.x"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2014.05.005"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzu005"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rasd.2013.01.002"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049732320937663"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2005.01544.x"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1177\/1362361310366571"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0036984"},{"key":"e_1_3_4_60_1","unstructured":"Ruberg J Kang S Sarawgi S et al. Regulating Together: An Exploration of the Caregiver Experience in a Caregiver-Assisted Group Intervention. Gatlinburg Conference on Research in ID\/DD; April 10 2025; San Diego CA 2025."},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2019.101751"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-015-2388-7"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/jclp.21951"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-021-05288-y"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-022-05461-x"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-018-3727-2"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579417001390"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.1097\/CHI.0b013e318179964f"},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrdd.20175"},{"key":"e_1_3_4_70_1","volume-title":"Vineland Adaptive Behavior Scales, Third Edition","author":"Sparrow SS","year":"2016","unstructured":"Sparrow SS, , Cicchetti DV, , Saulnier CA. Vineland Adaptive Behavior Scales, Third Edition. Bloomington, MN: NCS Pearson, Inc.; 2016."},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1080\/00332747.2018.1560584"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-017-3152-y"},{"key":"e_1_3_4_73_1","volume-title":"R: A Language and Environment for Statistical Computing","author":"Team RC","year":"2023","unstructured":"Team RC. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; 2023."},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kws185"},{"key":"e_1_3_4_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10567-009-0043-6"},{"key":"e_1_3_4_76_1","unstructured":"US Department of Health and Human Services. Social Determinants of Health Washington DC. n.d. Available from: https:\/\/health.gov\/healthypeople\/priority-areas\/social-determinants-health"},{"key":"e_1_3_4_77_1","volume-title":"Wechsler Abbreviated Scale of Intelligence\u2013Second Edition (WASI-II)","author":"Wechsler D","year":"2011","unstructured":"Wechsler D. Wechsler Abbreviated Scale of Intelligence\u2013Second Edition (WASI-II). San Antonio, TX: NCS Pearson; 2011."},{"key":"e_1_3_4_78_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-24277-4"},{"key":"e_1_3_4_79_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12939-019-1026-y"}],"container-title":["Journal of Child and Adolescent Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10445463261477348","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10445463261477348","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10445463261477348","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T04:40:15Z","timestamp":1792384815000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10445463261477348"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,23]]},"references-count":78,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,12,1]]}},"alternative-id":["10.1177\/10445463261477348"],"URL":"https:\/\/doi.org\/10.1177\/10445463261477348","relation":{},"ISSN":["1044-5463","1557-8992"],"issn-type":[{"value":"1044-5463","type":"print"},{"value":"1557-8992","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,23]]}}}