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We conducted qualitative interviews with 17 HIV providers from two urban public hospitals. We discovered that the limitations of the current state of medical knowledge, the severe side effects of HIV and HCV therapies, and the psychosocial vulnerability of HIV\/HCV-coinfected patients combined with their resistance to becoming informed about HCV posed significant challenges for providers. To contend with these challenges, providers incorporated key dimensions of patient-centered medicine in their practice, such as considering their patients\u2019 psychosocial profiles and the meaning patients assign to being coinfected, and finding ways to engage their patients in a therapeutic alliance.<\/jats:p>","DOI":"10.1177\/1049732311418248","type":"journal-article","created":{"date-parts":[[2011,8,9]],"date-time":"2011-08-09T02:20:27Z","timestamp":1312856427000},"page":"54-66","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Challenges Facing Providers Caring for HIV\/HCV-Coinfected Patients"],"prefix":"10.1177","volume":"22","author":[{"given":"Helen-Maria","family":"Lekas","sequence":"first","affiliation":[{"name":"Columbia University, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolynn","family":"Siegel","sequence":"additional","affiliation":[{"name":"Columbia University, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Leider","sequence":"additional","affiliation":[{"name":"North Bronx Health Care Network, Bronx, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,8,8]]},"reference":[{"key":"bibr1-1049732311418248","doi-asserted-by":"publisher","DOI":"10.1089\/108729104323038919"},{"key":"bibr2-1049732311418248","first-page":"269","volume":"17","author":"Balint E.","year":"1969","journal-title":"Journal of the Royal College of General Practitioners"},{"key":"bibr3-1049732311418248","doi-asserted-by":"publisher","DOI":"10.1016\/j.jana.2009.07.\/009"},{"key":"bibr4-1049732311418248","unstructured":"Centers for Disease Control and Prevention. 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