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An iterative qualitative analysis of 42 dyadic, family interviews ( N = 84) revealed (a) moments in the context of hereditary cancer that involved individual-centered and familial uncertainty appraisal and management, (b) family members\u2019 communication strategies to prompt relatives to engage familial uncertainty, and (c) the communicative (re)creation and negotiation of family models for uncertainty management. The findings illuminate tensions that individuals encounter across their lifespan as they appraise and manage uncertainty about hereditary cancer risks. This study extends uncertainty management theory to encompass familial uncertainty management and contributes insights useful for the management of hereditary cancer.<\/jats:p>","DOI":"10.1177\/10497323221090191","type":"journal-article","created":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T08:40:00Z","timestamp":1653640800000},"page":"1230-1245","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Managing Uncertainty for and With Family: Communication Strategies and Motivations in Familial Uncertainty Management for Hereditary Cancer"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1377-5705","authenticated-orcid":false,"given":"Gemme","family":"Campbell-Salome","sequence":"first","affiliation":[{"name":"Genomic Medicine Institute, Department of Population Health Sciences, Geisinger, Danville, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua B.","family":"Barbour","sequence":"additional","affiliation":[{"name":"Moody College of Communication, Department of Communication Studies, University of Texas at Austin, Austin, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,5,27]]},"reference":[{"key":"bibr1-10497323221090191","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(00)00112-X"},{"key":"bibr2-10497323221090191","first-page":"9","volume-title":"Uncertainty, information management, and disclosure decisions: Theories and Applications","author":"Babrow A. 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