{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T01:07:25Z","timestamp":1792112845805,"version":"4.4.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2010,5,27]],"date-time":"2010-05-27T00:00:00Z","timestamp":1274918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Hosp Palliat Care"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:p>\n                    Nausea and vomiting are often encountered in palliative care patients. Multiple medications are available to provide relief. However, several drug combinations are usually used to treat emesis. Current research has identified several receptors that trigger nausea and vomiting, hence the difficulty of using only 1 medication to provide relief. Olanzapine is a drug approved for treatment of schizophrenia and mania. It blocks multiple neurotransmitters dopaminergic, serotonergic, adrenergic (\u03b1\n                    <jats:sub>1<\/jats:sub>\n                    ), histaminergic, and muscarinic receptors. Most of these receptors are also involved in causing emesis. Studies have shown that olanzapine could be used to treat nausea and vomiting with promising results.\n                  <\/jats:p>","DOI":"10.1177\/1049909110369532","type":"journal-article","created":{"date-parts":[[2010,5,27]],"date-time":"2010-05-27T22:48:16Z","timestamp":1275000496000},"page":"432-434","source":"Crossref","is-referenced-by-count":17,"title":["Olanzapine for Nausea and Vomiting"],"prefix":"10.1177","volume":"27","author":[{"given":"Nerissa","family":"Licup","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, ETSU College of Medicine, Johnson City, TN, USA,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Baumrucker","sequence":"additional","affiliation":[{"name":"Department of Family Practice, ETSU college of Medicine, Johnson City, TN, USA, Palliative Medicine, Wellmont Health System, Kingsport, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,5,27]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1007\/s005200000151"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-005-0897-1"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/S0885-3924(03)00078-2"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1089\/109662103764978506"},{"issue":"12","key":"atypb5","first-page":"89","volume":"1","author":"Navari R.","year":"2003","journal-title":"J Support Oncol"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/S0885-3924(03)00143-X"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0b013e31816a0f07"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1517\/14728214.11.1.137"},{"issue":"6","key":"atypb9","first-page":"861","volume":"54","author":"O\u2019Brien C.","year":"2008","journal-title":"Can Fam Physician"},{"issue":"5","key":"atypb10","first-page":"1169","volume":"69","author":"Flake ZA","year":"2004","journal-title":"Am Fam Physician"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2006.08.003"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/S0885-3924(02)00391-3"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1081\/CNV-200029066"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-004-0755-6"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2354.2006.00760.x"},{"issue":"1","key":"atypb16","first-page":"64","volume":"1","year":"2003","journal-title":"J Support Oncol"}],"container-title":["American Journal of Hospice and Palliative Medicine\u00ae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1049909110369532","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1049909110369532","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:26:52Z","timestamp":1777368412000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1049909110369532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,27]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.1177\/1049909110369532"],"URL":"https:\/\/doi.org\/10.1177\/1049909110369532","relation":{},"ISSN":["1049-9091","1938-2715"],"issn-type":[{"value":"1049-9091","type":"print"},{"value":"1938-2715","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,27]]}}}