{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:04:41Z","timestamp":1792083881306,"version":"4.4.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T00:00:00Z","timestamp":1574035200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Hosp Palliat Care"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This systematic literature review explores the results of studies that have analyzed the association between inflammation and nutritional status in patients with cancer in palliative care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The bibliographic research was performed in May 2019, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Group guidelines. The inclusion criteria were papers that (1) had an online abstract available, (2) were original, (3) used a cohort or cross-sectional design, (4) involved patients with advanced cancer in palliative care, and (5) assessed the association between inflammation and nutritional status. The quality assessment was performed using the Newcastle-Ottawa Scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Nine studies were selected. Weight loss (WL; n = 7) was the most common nutritional marker employed and C-reactive protein (CRP; n = 6) was the most common inflammatory marker. There was considerable variability (39.0%-92.2%) in the proportion of patients who had WL in a 6-month period, while CRP &gt;5 mg\/dL was common in 45.3% to 73.9% of patients. Systemic inflammation was related to nutritional status, highlighting the relationship between CRP and WL and lean mass (LM). Patients with CRP &gt;10 mg\/L have been found to have a lower LM ( P &lt; .001) and a faster rate of loss of LM at a faster rate during the disease trajectory ( P = .030).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Nutritional status is associated with systemic inflammatory response. Inflammatory markers should be considered an additional parameter for the nutritional diagnosis of patients with cancer in palliative care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1049909119886833","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T05:12:09Z","timestamp":1574053929000},"page":"565-571","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":28,"title":["Systemic Inflammation and Nutritional Status in Patients on Palliative Cancer Care: A Systematic Review of Observational Studies"],"prefix":"10.1177","volume":"37","author":[{"given":"Luisa de Ara\u00fajo Fonseca","family":"Cordeiro","sequence":"first","affiliation":[{"name":"Professional Master\u2019s in Health, Laboratory Medicine and Forensic Technology, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago Huaytalla","family":"Silva","sequence":"additional","affiliation":[{"name":"Postgraduate of the National Cancer Institute Jos\u00e9 Alencar Gomes da Silva (INCA), Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00edvia Costa","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Search Group NutriPali, Nutritionist Palliative Care Unit, INCA, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Firmino Nogueira","family":"Neto","sequence":"additional","affiliation":[{"name":"Lipids Laboratory-LabLip, Faculty of Medical Sciences, UERJ, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,11,18]]},"reference":[{"key":"bibr1-1049909119886833","unstructured":"World Health Organization. GLOBOCAN 2012: Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012. 2012. http:\/\/globocan.iarc.fr\/Pages\/fact_sheets_cancer.aspx. Accessed January 2019."},{"key":"bibr2-1049909119886833","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21395"},{"key":"bibr3-1049909119886833","unstructured":"Economist Intelligence Unit. The 2015 Quality of Death Index: Ranking Palliative Care Across the World. London, United Kingdom: Economist Intelligence Unit. 2015. https:\/\/www.eiuperspectives.economist.com\/sites\/default\/files\/2015%20EIU%20Quality%20of%20Death%20Index%20Oct%2029%20FINAL.pdf. Accessed January 2019."},{"key":"bibr4-1049909119886833","volume-title":"Carvalho RCT, Parsons HA (orgs). 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