{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:02:07Z","timestamp":1777384927045,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100006364","name":"Institut National Du Cancer","doi-asserted-by":"publisher","award":["INCA_15908"],"award-info":[{"award-number":["INCA_15908"]}],"id":[{"id":"10.13039\/501100006364","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Hosp Palliat Care"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The death of a spouse due to cancer is highly distressing. While most adapt, a significant minority may develop Prolonged Grief Disorder (PGD) or experience Post-Traumatic Growth (PTG). Palliative sedation, particularly Continuous Deep Sedation Until Death (CDSUD), is used to alleviate refractory suffering, yet its psychological impact on bereaved spouses remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study examined whether exposure to CDSUD and alignment between end-of-life care and patient preferences influenced grief and PTG in bereaved spouses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional analysis was conducted using data from the AFTERSEDATIO project. Twenty-eight bereaved spouses (mean age = 64; 57% women) of cancer patients who received palliative care in French hospitals completed self-report questionnaires 3 months post-loss (T0). Measures included the Traumatic Grief Inventory\u2013Self Report, General Health Questionnaire, and Post-Traumatic Growth Inventory. Analyses included t-tests, Wilcoxon, and chi-square tests; the significance threshold was set at \u03b1 = .10.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No significant differences in grief, mental health, or PTG were observed between spouses whose partners received CDSUD (n = 21) and those who did not (n = 7). However, higher grief and distress were reported when patients had not explicitly requested sedation. Greater PTG\u2014especially in personal strength, spirituality, and new possibilities\u2014was associated with the absence of a stated wish to avoid suffering.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>While CDSUD itself did not significantly affect bereavement outcomes, the findings suggest that spouses\u2019 perceptions of alignment between the patient\u2019s end-of-life wishes and the care received may influence their adjustment to loss, underscoring the importance of clear communication and shared decision-making in palliative care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10499091251404906","type":"journal-article","created":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T17:56:28Z","timestamp":1764179788000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Continuous Deep Sedation Until Death on Grief and Post-Traumatic Growth in Bereaved Spouses: A Cross-Sectional Study"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9283-8051","authenticated-orcid":false,"given":"Livia","family":"Sani","sequence":"first","affiliation":[{"name":"SULISOM UR 3071, Universit\u00e9 de Strasbourg, Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7016-6426","authenticated-orcid":false,"given":"Yasmine","family":"Chemrouk","sequence":"additional","affiliation":[{"name":"SULISOM UR 3071, Universit\u00e9 de Strasbourg, Strasbourg, France"},{"name":"Palliative care Department, CHU Orl\u00e9ans, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marthe","family":"Ducos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Poulin","sequence":"additional","affiliation":[{"name":"Institute for Advanced Mathematical Research, University of Strasbourg, Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Gauthier","sequence":"additional","affiliation":[{"name":"Palliative care Department, CHU Orl\u00e9ans, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Fr\u00e9d\u00e9rique","family":"Bacqu\u00e9","sequence":"additional","affiliation":[{"name":"SULISOM UR 3071, Universit\u00e9 de Strasbourg, Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"key":"e_1_3_8_2_2","unstructured":"Common Cancer Sites - Cancer Stat Facts. 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