{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:03:10Z","timestamp":1777384990738,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Hosp Palliat Care"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Delirium is prevalent in Palliative Care patients and often induces distress in family members. Improving knowledge in this field will enable a more efficient approach to this problem, thereby helping patients and their families.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate the distress in family members of patients with delirium hospitalized in an Acute Palliative Care Unit (APCU).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>An anonymous survey was applied to caregivers 3\u00a0days after the identification of delirium. Validated instruments were used to identify the symptoms perceived by family members and their level of distress related to the delirium episode.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventy caregivers (of 48 patients) were included; the patients had a median survival of 12\u00a0days. Family members recognized the signs of delirium, with nearly 80% reporting severe distress. Younger caregiver age (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05), higher delirium severity (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01), hyperactive delirium subtype (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) and survival (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) were strongly associated with severe distress. In the multivariate analysis, only survival maintained statistical significance (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The severe distress experienced by caregivers underscores the need for a family-centered approach to prevent and support their suffering. Our results highlight the role of family in the recognition of delirium, working alongside the therapeutic team. Future research should provide longer follow-up of carers\u2019 distress, compare family members of patients with and without delirium and similar survival rates, and evaluate the impact of communication on the distress experienced by these families.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10499091261444005","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T10:27:53Z","timestamp":1776421673000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Distress in Family Members of Patients With Delirium in an Acute Palliative Care Unit \u2013 A Cross-Sectional Survey Study"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3734-4013","authenticated-orcid":false,"given":"Teresa","family":"Tavares","sequence":"first","affiliation":[{"name":"Unidade Local de Sa\u00fade S\u00e3o Jo\u00e3o"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Paiva","sequence":"additional","affiliation":[{"name":"Unidade Local de Sa\u00fade S\u00e3o Jo\u00e3o"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasco","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Unidade Local de Sa\u00fade S\u00e3o Jo\u00e3o"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Queir\u00f3s","sequence":"additional","affiliation":[{"name":"Unidade Local de Sa\u00fade S\u00e3o Jo\u00e3o"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Vieira","sequence":"additional","affiliation":[{"name":"Unidade Local de Sa\u00fade S\u00e3o Jo\u00e3o"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Maia","sequence":"additional","affiliation":[{"name":"Unidade Local de Sa\u00fade S\u00e3o Jo\u00e3o"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"M\u00f4\u00e7o","sequence":"additional","affiliation":[{"name":"Unidade Local de Sa\u00fade de Matosinhos"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delfim","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Unidade Local de Sa\u00fade S\u00e3o Jo\u00e3o"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edna","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Unidade Local de Sa\u00fade S\u00e3o Jo\u00e3o"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Abelha","sequence":"additional","affiliation":[{"name":"Unidade Local de Sa\u00fade S\u00e3o Jo\u00e3o"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,17]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/0269216319854944"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1478951508000242"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1191\/0269216304pm879oa"},{"issue":"1","key":"e_1_3_4_5_2","first-page":"Cd004770","article-title":"Drug therapy for delirium in terminally ill adults","volume":"1","author":"Finucane AM","year":"2020","unstructured":"Finucane AM, Jones L, Leurent B, et al. 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