{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T21:58:23Z","timestamp":1780783103981,"version":"3.54.1"},"reference-count":46,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:00:00Z","timestamp":1777680000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:00:00Z","timestamp":1777680000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"publisher","award":["18861"],"award-info":[{"award-number":["18861"]}],"id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Hosp Palliat Care"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Many patients with incurable cancer are expected to live for a considerable period of time, yet with the knowledge of their disease\u2019s inevitable end-of-life outcome. This duality can lead to existential concerns. A single one-hour meaning-making conversation was developed in which a patient explores their sources of meaning together with a spiritual counselor.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To explore how patients experience and benefit from a conversation aimed at supporting meaning-making, in order to inform further refinement of this intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>We conducted a formative mixed method pilot study. Evaluation interviews assessed patients\u2019 experience and reported benefits. A reflexive thematic analysis was conducted. Key themes were compared and contrasted by intervention timing and patients\u2019 experience of existential concerns. Validated questionnaires were administered to assess patients\u2019 existential wellbeing, problems, and needs pre- and post-intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting\/Participants<\/jats:title>\n                    <jats:p>Twenty-one patients with advanced solid malignancies and a prognosis &gt;1 year participated at two different hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All patients experiencing existential concerns appreciated the meaning-making conversation and reported benefits, such as reflection, validation, insight and actions related to sources of meaning. Half of the those not experiencing existential concerns reported no benefits, and some reported a negative experience. Quantitative data suggest a decrease in most existential problems and needs post-intervention. Existential wellbeing increased post-intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A meaning-making conversation can support the process of meaning-making for patients living long-term with incurable cancer. Refinement of the intervention should focus on targeting patients experiencing existential concerns.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10499091261444921","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:04:21Z","timestamp":1777716261000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["A Meaning-Making Conversation: A Formative Mixed Method Pilot Study of a Brief Intervention for Patients Living Long-Term With Incurable Cancer"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9321-4272","authenticated-orcid":false,"given":"Anna","family":"Visser","sequence":"first","affiliation":[{"name":"Amsterdam UMC"},{"name":"Cancer Center Amsterdam, Cancer Treatment and Quality of Life, Amsterdam, the 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