{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T12:07:11Z","timestamp":1789214831345,"version":"build-2803163510"},"reference-count":39,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Thyroid\u00ae"],"published-print":{"date-parts":[[2026,10,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Thermal ablation has emerged as a minimally invasive alternative for low-risk papillary thyroid cancer (PTC). However, data from Latin America remain scarce. This multicenter study evaluated the early efficacy and safety of thermal ablation for low-risk PTC across multiple Latin American centers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective cohort study including 251 patients with 252 tumors (T1N0M0 PTC, \u22642 cm) treated with ultrasound-guided radiofrequency ablation (RFA) at 12 centers across 6 Latin American countries from January 2019 to June 2025. Primary outcomes were complete tumor disappearance, disease progression, and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Median age was 45.5 years (interquartile range [IQR]: 36.5\u201356), with 74.2% female patients. Median tumor size was 6.7 mm (IQR: 5\u20138); 92.1% were T1a (\u226410 mm). After a median follow-up of 18 months (IQR 12\u201324, range 12\u201372), complete tumor disappearance was achieved in 89.7% overall (226\/252), reaching 97.0% in tumors with \u226518 months and 100% with \u226536 months of follow-up. Tumor persistence was observed in 10.3% (26\/252) at last follow-up, with no lymph node or distant metastases. The overall complication rate was 2.4% (6\/252), all consisting of transient dysphonia. On multivariable analysis, tumor size &gt;10 mm was independently associated with a lower likelihood of complete tumor disappearance (adjusted odds ratios [OR] 0.23 [CI: 0.07\u20130.78]), whereas follow-up &gt;12 months was associated with a higher likelihood (adjusted OR: 11.33 [CI: 3.61\u201335.6]). A supplementary\n                      <jats:italic toggle=\"yes\">post hoc<\/jats:italic>\n                      analysis suggested a possible association between higher general operator volume (\u2265250 RFA procedures) and complete disappearance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>RFA demonstrates excellent efficacy and acceptable safety for T1a low-risk PTC in Latin American patients, with outcomes comparable with other series, supporting it as a viable alternative to surgery or active surveillance in selected patients. Efficacy for T1b tumors was lower and based on a small number of cases; ablation of T1b disease should therefore be regarded as requiring further investigation, ideally within the framework of a clinical trial.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10507256261475837","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T08:46:32Z","timestamp":1786005992000},"page":"1053-1062","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Early Outcomes of Thermal Ablation for Low-Risk Papillary Thyroid Cancer: A Multicenter Study from Latin American Interventional Thyroidology Association (LAITA)"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7206-9037","authenticated-orcid":false,"given":"Juan Pablo","family":"Due\u00f1as","sequence":"first","affiliation":[{"name":"Division of Endocrine Surgery, Department of Surgery, Integral Endocrine Surgery Clinic, Torre Medica Oviedo, Medellin, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalia","family":"Buitrago-G\u00f3mez","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Cl\u00ednica de Occidente, Cali, Colombia."},{"name":"Fundaci\u00f3n San Jos\u00e9 de Buga, Buga, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Rahal","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Thyroid Imaging and Intervention Center, Hospital Israelita Albert Einstein, S\u00e3o Paulo, Brazil."},{"name":"Interventional Radiology Division, Sociedade Paulista de Radiologia (S.P.R.), S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Higinio","family":"Steck","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology IOU (Institute of Otolaryngology Head and Neck Surgery Unicamp), University of Campinas, Campinas, Brazil."},{"name":"Head and Neck Sector Otolaryngology Division, IOU (Institute of Otolaryngology Head and Neck Surgery Unicamp), University of Campinas, Campinas, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Philippi","family":"de los Santos","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Hospital Universitario de la Universidad Federal de Santa Catarina, Grupo NICAP Florian\u00f3polis, Santa Catarina, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristhian","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery Department, Institute of Thyroid and Head and Neck Diseases (ITECC), Quito, Ecuador."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emerson","family":"Favero","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Clinica Cirurgia VI\u2014Universidade de Mogi das Cruzes- Faculdade das Am\u00e9ricas, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"De Cicco","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Instituto de C\u00e2ncer Dr Arnaldo, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo G.","family":"Rangel","sequence":"additional","affiliation":[{"name":"Division of Otorhinolaryngology\u2014Head and Neck Surgery, State University of Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Godoy","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Clinica Tiroides, Quito, Ecuador."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Horvath","sequence":"additional","affiliation":[{"name":"Radiology Department, Thyroid Board, Clinica Alemana, Facultad de Medicina 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