{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T23:49:49Z","timestamp":1782949789380,"version":"3.54.5"},"reference-count":38,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,1,26]],"date-time":"2025-01-26T00:00:00Z","timestamp":1737849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Back and Musculoskeletal Rehabilitation"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Poor posture from work or lifestyle habits is a common cause of low back soreness and discomfort. This study investigates the potential of Rhuleave-K, a turmeric-Boswellia formulation for managing these symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the efficacy of Rhuleave-K (500 mg) over 15 days in alleviating posture-related low back soreness and discomfort in human participants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This randomized, placebo-controlled, double-blinded, parallel arm study involved 52 subjects aged 18\u201370 years, with an equal male to female ratio of 1:1, and a 15 days intervention period. The inclusion criteria were a posture-related low back soreness and discomfort for at least 2\u20133 weeks with a pain intensity of greater than or equal to 5 on numerical rating scale. The primary outcome measure was a pain intensity difference from baseline to day 7 and day 15. Secondary outcome measures were a categorical pain relief scale and Oswestry disability index (ODI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There was a significant decrease in the pain intensity (p\u2009&lt;\u20090.001) compared to placebo at the end of 15 days of study in the Rhuleave-K group. After 7 days of supplementation of Rhuleave-K, there was a 56% reduction in pain intensity and by the end of the study, there was 98.5% reduction. In the responder profile of those having greater than or equal to 50% of max total pain relief, all 26 was in Rhuelave-K group and 3 were in placebo group. The ODI had significant 27% and 98% reduction in the disability index at day 7 and 15 respectively for Rhuleave-K group and placebo group had 1% and 3% change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Posture-related low back soreness and discomfort was significantly reduced by Rhuleave-K at 500 mg dose. It is hence evident from this study's outcome that the Rhuleave-K can be a safe and effective alternative for the short-term management of lower back discomfort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10538127241296343","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T23:25:16Z","timestamp":1738106716000},"page":"494-505","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["The effect of turmeric-Boswellia formulation (Rhuleave-K) in posture-related low back soreness and discomfort: A randomized double blinded placebo controlled trial"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5718-4767","authenticated-orcid":false,"given":"Ajay","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Nirmal Hospital, Jhansi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alok","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Mewa Choudhary Memorial Hospital, Jhansi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,1,26]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s43161-021-00052-w"},{"key":"e_1_3_4_3_2","first-page":"105","article-title":"Definicije do dijagnoze. 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