{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:39:17Z","timestamp":1777466357592,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Application of micro-non-invasive regenerative medicine technology for bone and muscle disease visualization","award":["2022YJ03"],"award-info":[{"award-number":["2022YJ03"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Back and Musculoskeletal Rehabilitation"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigates the value of super microvascular imaging (SMI) and shear wave elastography (SWE) in evaluating the relationship between synovial tissues and disease severity in knee osteoarthritis (KOA) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Patients with KOA who visited our hospital between August 2022 and May 2023 were enrolled. WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) scores, X-ray images (Kellgren-Lawrence grading), power Doppler imaging (PDI), SMI, and SWE were evaluated for each patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 54 patients were enrolled. SMI detected more synovial blood flow than PDI (79.62% vs. 62.96%,\n                      <jats:italic toggle=\"yes\">p\u2009<\/jats:italic>\n                      &lt;\u20090.001). SMI upgraded 22.22% of PDI from level 0 to level 1, 31.48% from level 1 to level 2, and 9.26% from level 2 to level 3. There was a positive correlation between WOMAC scores and Kellgren-Lawrence grading (KLG), (r\u2009=\u20090.79,\n                      <jats:italic toggle=\"yes\">p\u2009<\/jats:italic>\n                      &lt;\u20090.001). PDI showed no significant correlation with WOMAC scores (r\u2009=\u20090.26,\n                      <jats:italic toggle=\"yes\">p\u2009<\/jats:italic>\n                      =\u20090.06) or KLG (r\u2009=\u20090.12,\n                      <jats:italic toggle=\"yes\">p\u2009<\/jats:italic>\n                      =\u20090.40). SMI also showed no significant correlation with WOMAC scores (r\u2009=\u20090.26,\n                      <jats:italic toggle=\"yes\">p\u2009<\/jats:italic>\n                      =\u20090.05) or KLG (r\u2009=\u20090.06,\n                      <jats:italic toggle=\"yes\">p\u2009<\/jats:italic>\n                      =\u20090.67). However, A significant correlation was showcased between PDI (r\u2009=\u20090.38,\n                      <jats:italic toggle=\"yes\">p\u2009<\/jats:italic>\n                      =\u20090.04), SMI (r\u2009=\u20090.47,\n                      <jats:italic toggle=\"yes\">p\u2009<\/jats:italic>\n                      &lt;\u20090.001) and the WOMAC pain scores. Additionally, SWE exhibited significant positive correlations with WOMAC scores (r\u2009=\u20090.74,\n                      <jats:italic toggle=\"yes\">p\u2009<\/jats:italic>\n                      &lt;\u20090.001) and KLG (r\u2009=\u20090.84,\n                      <jats:italic toggle=\"yes\">p\u2009<\/jats:italic>\n                      &lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In patients with KOA, SMI improved the detection of synovial blood flow and is significantly superior to PDI, offering a more sensitive tool for assessing synovial blood flow. SWE of synovial tissue showed a positive correlation with disease severity, providing a novel tool for assessing the severity of the disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10538127251328901","type":"journal-article","created":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T06:20:43Z","timestamp":1745043643000},"page":"1342-1351","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The value of super microvascular imaging and shear wave elastography in evaluating synovial lesions in knee osteoarthritis"],"prefix":"10.1177","volume":"38","author":[{"given":"Min","family":"Jin","sequence":"first","affiliation":[{"name":"Department of Medical Ultrasound, The Second People's Hospital of Hunan Province, 427 FuRongZhong Road, ChangSha, 410000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Mi","sequence":"additional","affiliation":[{"name":"Department of Orthopedist, The Second People's Hospital of Hunan Province, 427 FuRongZhong Road, ChangSha, 410000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han-Wen","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Physiatry, The First Affiliated Hospital of Hunan University of Medicine, 225 YuShi Road, HuaiHua 418000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fu-Li","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Yueyang Central Hospital, 39 DongMaoLing Road, Yueyang, 414000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You-Yuan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, The Second People's Hospital of Hunan Province, 427 FuRongZhong Road, ChangSha, 410000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Juan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, The Second People's Hospital of Hunan Province, 427 FuRongZhong Road, ChangSha, 410000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, The Second People's Hospital of Hunan Province, 427 FuRongZhong Road, ChangSha, 410000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Yueyang Central Hospital, 39 DongMaoLing Road, Yueyang, 414000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,4,17]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.942626"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-024-06885-9"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000350"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2022.03.004"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-020-00949-w"},{"key":"e_1_3_3_7_2","first-page":"41","article-title":"Differential diagnosis of inflammatory arthropathies by musculoskeletal ultrasonography: a systematic literature review","volume":"7","author":"Sakellariou G","year":"2020","unstructured":"Sakellariou G, Scir\u00e8 CA, Adinolfi A, et al. 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