{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T03:28:59Z","timestamp":1782444539282,"version":"3.54.5"},"reference-count":81,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Guangdong Bureau of Traditional Chinese Medicine Project: Yang Wenhui Famous medical studio."},{"name":"Guangzhou Science and Technology Bureau Project","award":["202102010489"],"award-info":[{"award-number":["202102010489"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Back and Musculoskeletal Rehabilitation"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>As a contemporary acupuncture technique combined with modern anatomy and biomechanics, acupotomy was widely used in clinical treatment of knee osteoarthritis (KOA). This article aims to evaluate the advantages and potential of acupotomy of KOA and to provide a reference for clinical decision-making.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>We conducted a comprehensive search across four databases of ancient Chinese classics to trace the historical development of acupotomy. Seven databases were searched for the meta-analysis of Randomized controlled trials (RCTs) that met the criteria to evaluate the clinical efficacy of acupotomy for KOA. Furthermore, we reviewed potential mechanisms underlying acupotomy treatment for KOA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Acupotomy originated from traditional acupuncture \u201cNine Needles\u201d in China ancient books 2000 years ago, which had advantages in the treatment of muscle and bone related diseases. The results of the meta-analysis following PRISMA2020 showed that acupotomy was helpful for pain relief and improvement of knee mobility in KOA. Experiments showed that acupotomy may treat KOA through a variety of mechanisms, such as inhibiting the expression of inflammatory factors, promoting the proliferation of chondrocytes, affecting the degradation and synthesis of extracellular matrix, and adjusting the mechanical balance of the knee joint.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The results of this meta-analysis suggest that the use of acupotomy can effectively improve the pain and increase the range of motion of KOA. The experimental data showed that acupotomy may play a therapeutic role by inhibiting inflammatory factors and changing the mechanical balance of the knee joint. All these can prove that acupotomy treatment has a good prospect.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10538127251349150","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T02:20:54Z","timestamp":1750386054000},"page":"34-52","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Acupotomy for knee osteoarthritis: Literature review and meta-analysis"],"prefix":"10.1177","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6998-5715","authenticated-orcid":false,"given":"Anqi","family":"Di","sequence":"first","affiliation":[{"name":"School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China"},{"name":"Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danghan","family":"Xu","sequence":"additional","affiliation":[{"name":"Rehabilitation Center, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6894-6918","authenticated-orcid":false,"given":"Anxin","family":"Zhang","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1208-2072","authenticated-orcid":false,"given":"Zhaoxi","family":"Liu","sequence":"additional","affiliation":[{"name":"Guangzhou Medical University Affiliated Traditional Chinese Medicine Hospital, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiang","family":"Lin","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanbu","family":"Wang","sequence":"additional","affiliation":[{"name":"Rehabilitation Center, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"He","sequence":"additional","affiliation":[{"name":"Rehabilitation Center, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Zheng","sequence":"additional","affiliation":[{"name":"Rehabilitation Center, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Fang","sequence":"additional","affiliation":[{"name":"Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,6,19]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22052619"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11655-015-2432-7"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22721"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24131"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.09.010"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.39465"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16234701"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2020.09.001"},{"issue":"1","key":"e_1_3_3_10_2","doi-asserted-by":"crossref","DOI":"10.1016\/j.otsr.2017.04.017","article-title":"Quality of life after total knee arthroplasty","volume":"104","author":"Canovas F","year":"2018","unstructured":"Canovas F, Dagneaux L. 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