{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T06:51:56Z","timestamp":1780555916324,"version":"3.54.1"},"reference-count":55,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T00:00:00Z","timestamp":1753056000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Back and Musculoskeletal Rehabilitation"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Low back pain (LBP) is one of the most common causes of disability worldwide. Although the etiology of LBP is varied, mechanical and inflammatory stimuli might involve the lumbar region, determining neurological symptoms and even radicular pain, often varying with posture.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      This randomized controlled trial (RCT) aimed to evaluate the efficacy of Oxygen-Ozone (O\n                      <jats:sub>2<\/jats:sub>\n                      O\n                      <jats:sub>3<\/jats:sub>\n                      ) injections and Proprioceptive Neuromuscular Facilitation (PNF) in pain relief and functioning in LBP, in comparison with a Control Group treated with O\n                      <jats:sub>2<\/jats:sub>\n                      O\n                      <jats:sub>3<\/jats:sub>\n                      and Back School program.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We included 86 patients randomly assigned to two groups affected by LBP, with a Numerical Rating Scale (NRS) scale &gt;4. There were 8 dropouts, for a total of 78 patients enrolled. All the patients underwent 8 injections of O\n                      <jats:sub>2<\/jats:sub>\n                      O\n                      <jats:sub>3<\/jats:sub>\n                      , once a week, with a concentration of 20\u2005\u03bcg\/mL, administered into the paravertebral musculature at L4-L5 and L5-S1 bilaterally. Subsequently, the experimental group underwent PNF treatment, while the control group received Back School techniques, 3 times\/week for 4 weeks. Outcome measures included NRS, Oswestry Disability Index (ODI), EuroQol-5-Dimensions-3-Levels (EQ5D3L). We used: Independent t-test for between-group analysis, paired t-test for within-group analysis; ANOVA for repeated-measures analysis along the different time-points.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Both groups showed significant improvements in NRS, ODI after O\n                      <jats:sub>2<\/jats:sub>\n                      O\n                      <jats:sub>3<\/jats:sub>\n                      injections (T1, p\u2009&lt;\u20090.005). Physical therapy with O\n                      <jats:sub>2<\/jats:sub>\n                      O\n                      <jats:sub>3<\/jats:sub>\n                      demonstrated improvements in all outcomes (p\u2009&lt;\u20090.005), with greater efficacy in the PNF-group, particularly in NRS and ODI (\u0394T0-T2, p\u2009&lt;\u20090.005).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This RCT demonstrated the efficacy of a combined treatment, based on O\n                      <jats:sub>2<\/jats:sub>\n                      O\n                      <jats:sub>3<\/jats:sub>\n                      injections and PNF or Back-School, in improving pain, and functioning in LBP, with major findings in PNF management.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10538127251360867","type":"journal-article","created":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T10:37:07Z","timestamp":1753094227000},"page":"228-241","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of oxygen-ozone therapy and proprioceptive neuromuscular facilitation on pain and disability in patients affected by acute or subacute low back pain: A randomized controlled trial"],"prefix":"10.1177","volume":"39","author":[{"given":"Alessandro","family":"de Sire","sequence":"first","affiliation":[{"name":"Physical and Rehabilitative Medicine, Department of Medical and Surgical Sciences, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"},{"name":"Research Center on Musculoskeletal Health, MusculoSkeletalHealth@UMG, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Parente","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitative Medicine, Department of Medical and Surgical Sciences, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Prestifilippo","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitative Medicine, Department of Medical and Surgical Sciences, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Cocco","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitative Medicine, Department of Medical and Surgical Sciences, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"},{"name":"Physical and Rehabilitative Medicine, ASL Cagliari, Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Fasano","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitative Medicine, Department of Medical and Surgical Sciences, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Racinelli","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitative Medicine, Department of Medical and Surgical Sciences, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Reggiani","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitative Medicine, Casa di Cura \u201cLa Madonnina\u201d, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambrogio","family":"Vimercati","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitative Medicine, Department of Medical and Surgical Sciences, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Marotta","sequence":"additional","affiliation":[{"name":"Research Center on Musculoskeletal Health, MusculoSkeletalHealth@UMG, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"},{"name":"Physical and Rehabilitative Medicine Unit, Department of Experimental and Clinical Medicine, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Ammendolia","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitative Medicine, Department of Medical and Surgical Sciences, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"},{"name":"Research Center on Musculoskeletal Health, MusculoSkeletalHealth@UMG, University of Catanzaro \u201cMagna Graecia\u201d, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,7,21]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30925-9"},{"key":"e_1_3_3_3_2","article-title":"Implication of two different doses of intradiscal Ozone-Oxygen injection upon the pain alleviation in patients with low back pain: a randomized, single-blind study","volume":"21","author":"Elawamy A","unstructured":"Elawamy A, Kamel EZ, Hassanien M, et al. Implication of two different doses of intradiscal Ozone-Oxygen injection upon the pain alleviation in patients with low back pain: a randomized, single-blind study. Pain Physician 2018 Jan; 21: E25\u2013E31.","journal-title":"Pain Physician"},{"key":"e_1_3_3_4_2","article-title":"Global, regional, and national burden of low back pain, 1990\u20132020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021","volume":"5","author":"Ferreira ML","unstructured":"Ferreira ML, De Luca K, Haile LM, et al. Global, regional, and national burden of low back pain, 1990\u20132020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol 2023 Jun; 5: e316\u2013e329.","journal-title":"Lancet Rheumatol"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.3233\/BMR-215004"},{"key":"e_1_3_3_6_2","first-page":"119","article-title":"Low back pain related to a sacral insufficiency fracture: role of paravertebral oxygen-ozone therapy in a paradigmatic case of nociplastic pain","volume":"34","author":"de Sire A","year":"2019","unstructured":"de Sire A, Baricich A, Minetto MA, et al. Low back pain related to a sacral insufficiency fracture: role of paravertebral oxygen-ozone therapy in a paradigmatic case of nociplastic pain. Funct Neurol 2019; 34: 119\u2013122.","journal-title":"Funct Neurol"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001384"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000507"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3233\/BMR-245005"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.7326\/M16-2367"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.25790"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/biom11030356"},{"key":"e_1_3_3_13_2","first-page":"467","article-title":"Treatment of radiculopathies: a study of efficacy and tollerability of paravertebral oxygen-ozone injections compared with pharmacological anti-inflammatory treatment","volume":"26","author":"Melchionda D","year":"2012","unstructured":"Melchionda D, Milillo P, Manente G, et al. Treatment of radiculopathies: a study of efficacy and tollerability of paravertebral oxygen-ozone injections compared with pharmacological anti-inflammatory treatment. J Biol Regul Homeost Agents 2012; 26: 467\u2013474.","journal-title":"J Biol Regul Homeost Agents"},{"key":"e_1_3_3_14_2","first-page":"6034","article-title":"Oxygen-ozone therapy for the treatment of low back pain: a systematic review of randomized controlled trials","volume":"25","author":"Sconza C","unstructured":"Sconza C, Leonardi G, Kon E, et al. Oxygen-ozone therapy for the treatment of low back pain: a systematic review of randomized controlled trials. Eur Rev Med Pharmacol Sci 2021 Oct; 25: 6034\u20136046.","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.3233\/BMR-181294"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181a3c18d"},{"key":"e_1_3_3_17_2","first-page":"31","article-title":"An observational retrospective\/horizontal study to compare oxygen-ozone therapy and\/or global postural re-education in complicated chronic low back pain","volume":"29","author":"Apuzzo D","year":"2014","unstructured":"Apuzzo D, Giotti C, Pasqualetti P, et al. An observational retrospective\/horizontal study to compare oxygen-ozone therapy and\/or global postural re-education in complicated chronic low back pain. Funct Neurol 2014; 29: 31\u201339.","journal-title":"Funct Neurol"},{"key":"e_1_3_3_18_2","first-page":"41","article-title":"Intramuscular oxygen-ozone therapy in the treatment of low back pain","volume":"89","author":"Biazzo A","unstructured":"Biazzo A, Corriero AS, Confalonieri N. Intramuscular oxygen-ozone therapy in the treatment of low back pain. Acta Bio Medica Atenei Parm 2018 Mar 27; 89: 41\u201346.","journal-title":"Acta Bio Medica Atenei Parm"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23052528"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24108788"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctcp.2021.101505"},{"key":"e_1_3_3_22_2","article-title":"Developing the Kabat concept: progressive modular rebalancing system (RMP) with neurokinetic facilitations","volume":"6","author":"Monari G","year":"2016","unstructured":"Monari G, Sinibaldi E, De Petris V, et al. Developing the Kabat concept: progressive modular rebalancing system (RMP) with neurokinetic facilitations. J Nov Physiother [Internet] 2016 [cited 2025 Mar 6]; 6. https:\/\/www.omicsgroup.org\/journals\/developing-the-kabat-concept-progressive-modular-rebalancing-systemrmp-with-neurokinetic-facilitations-2165-7025-1000312.php?aid=81129","journal-title":"J Nov Physiother [Internet]"},{"key":"e_1_3_3_23_2","article-title":"The effectiveness of manual therapy and proprioceptive neuromuscular facilitation compared to kinesiotherapy: a four-arm randomized controlled trial","volume":"57","author":"Zaworski K","unstructured":"Zaworski K, Latosiewicz R. The effectiveness of manual therapy and proprioceptive neuromuscular facilitation compared to kinesiotherapy: a four-arm randomized controlled trial. Eur J Phys Rehabil Med [Internet] 2021 May [cited 2025 Mar 6]; 57. https:\/\/www.minervamedica.it\/index2.php?show=R33Y2021N02A0280","journal-title":"Eur J Phys Rehabil Med [Internet]"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.27.1629"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.27.3237"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199612010-00011"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjpt.2018.11.006"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1123\/jsr.2023-0244"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199712150-00020"},{"key":"e_1_3_3_30_2","article-title":"Long-Term effects of specific stabilizing exercises for first-episode low back pain","volume":"26","author":"Hides JA","unstructured":"Hides JA, Jull GA, Richardson CA. Long-Term effects of specific stabilizing exercises for first-episode low back pain. Spine 2001 Jun; 26: e243\u2013e248.","journal-title":"Spine"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbmt.2024.03.049"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-022-06179-y"},{"key":"e_1_3_3_33_2","first-page":"1169","article-title":"Treating myofascial pain with dry needling: a systematic review for the best evidence-based practices in low back pain","volume":"81","author":"Dach F","unstructured":"Dach F, Ferreira KS. Treating myofascial pain with dry needling: a systematic review for the best evidence-based practices in low back pain. Arq Neuropsiquiatr 2023 Dec; 81: 1169\u20131178.","journal-title":"Arq Neuropsiquiatr"},{"key":"e_1_3_3_34_2","article-title":"Effectiveness of proprioceptive neuromuscular facilitation on pain intensity and functional disability in patients with low back pain: A systematic review and meta-analysis","volume":"8","author":"Pourahmadi M","unstructured":"Pourahmadi M, Sahebalam M, Bagheri R. Effectiveness of proprioceptive neuromuscular facilitation on pain intensity and functional disability in patients with low back pain: A systematic review and meta-analysis. Arch Bone Jt Surg [Internet] 2020 Jul [cited 2025 May 17]; 8. https:\/\/doi.org\/10.22038\/abjs.2020.45455.2245","journal-title":"Arch Bone Jt Surg [Internet]"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17165916"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198101000-00022"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2014.03.005"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2013.04.020"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1080\/10833196.2016.1216764"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjpt.2018.10.005"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-200636110-00002"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.2478\/v10078-012-0011-y"},{"key":"e_1_3_3_43_2","article-title":"Proprioceptive neuromuscular facilitation training induced alterations in muscle fibre type and cross sectional area","volume":"39","author":"Kofotolis N","unstructured":"Kofotolis N, Vrabas IS, Vamvakoudis E, et al. Proprioceptive neuromuscular facilitation training induced alterations in muscle fibre type and cross sectional area. Br J Sports Med 2005 Mar; 39: e11\u2013e11.","journal-title":"Br J Sports Med"},{"key":"e_1_3_3_44_2","article-title":"Clinically significant changes in pain along the pain intensity numerical rating scale in patients with chronic low back pain. Li Y, editor","volume":"15","author":"Suzuki H","unstructured":"Suzuki H, Aono S, Inoue S, et al. Clinically significant changes in pain along the pain intensity numerical rating scale in patients with chronic low back pain. Li Y, editor. Plos One 2020 Mar 3; 15: e0229228.","journal-title":"Plos One"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200011150-00017"},{"key":"e_1_3_3_46_2","article-title":"Use of the oswestry disability Index in ankylosing spondylitis","volume":"69","author":"Aytekin E","year":"2023","unstructured":"Aytekin E, Ozgonenel L, Coskun H, et al. Use of the oswestry disability Index in ankylosing spondylitis. Rev Assoc M\u00e9dica Bras 2023; 69: e20230927.","journal-title":"Rev Assoc M\u00e9dica Bras"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2012.10.030"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001506"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjan.2019.06.007"},{"key":"e_1_3_3_50_2","article-title":"Oswestry Disability Index Roland-Morris Disability Questionnaire and Quebec Back Pain Disability Scale: Responsiveness and minimal clinically important changes in Iranian people with lumbar disc herniation following physiotherapy","author":"Ghaderi Niri H","unstructured":"Ghaderi Niri H, Ghanavati T, Mostafaee N, et al. Oswestry Disability Index Roland-Morris Disability Questionnaire and Quebec Back Pain Disability Scale: Responsiveness and minimal clinically important changes in Iranian people with lumbar disc herniation following physiotherapy. Arch Bone Jt Surg [Internet] 2023 Dec [cited 2025 Mar 6]. (Online First). https:\/\/doi.org\/10.22038\/abjs.2023.72246.3366","journal-title":"Arch Bone Jt Surg [Internet]"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1179\/174328810X12647087218677"},{"key":"e_1_3_3_52_2","article-title":"Effectiveness of proprioceptive neuromuscular facilitation on pain intensity and functional disability in patients with low back pain: A systematic review and meta-analysis","volume":"8","author":"Pourahmadi M","unstructured":"Pourahmadi M, Sahebalam M, Bagheri R. Effectiveness of proprioceptive neuromuscular facilitation on pain intensity and functional disability in patients with low back pain: A systematic review and meta-analysis. Arch Bone Jt Surg [Internet] 2020 Jul [cited 2025 May 10]; 8. https:\/\/doi.org\/10.22038\/abjs.2020.45455.2245","journal-title":"Arch Bone Jt Surg [Internet]"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.3390\/jpm14030272"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.4103\/err.err_43_17"},{"key":"e_1_3_3_55_2","article-title":"EuroQol-5D (EQ-5D): an instrument for measuring quality of life","volume":"78","author":"Balestroni G","unstructured":"Balestroni G, Bertolotti G. EuroQol-5D (EQ-5D): an instrument for measuring quality of life. Monaldi Arch Chest Dis [Internet] 2015 Dec 1 [cited 2025 May 10]; 78. http:\/\/www.monaldi-archives.org\/index.php\/macd\/article\/view\/121","journal-title":"Monaldi Arch Chest Dis [Internet]"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1097\/CORR.0000000000000419"}],"container-title":["Journal of Back and Musculoskeletal Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10538127251360867","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10538127251360867","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10538127251360867","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:28:31Z","timestamp":1777382911000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10538127251360867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,21]]},"references-count":55,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1177\/10538127251360867"],"URL":"https:\/\/doi.org\/10.1177\/10538127251360867","relation":{},"ISSN":["1053-8127","1878-6324"],"issn-type":[{"value":"1053-8127","type":"print"},{"value":"1878-6324","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,21]]}}}