{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T02:55:56Z","timestamp":1793328956247,"version":"4.5.0"},"reference-count":25,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Back and Musculoskeletal Rehabilitation"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cerebral palsy (CP) is a leading cause of physical disability in children, characterized by impaired motor function and muscle weakness. Progressive resistance training (PRT) has emerged as a potential strategy for improving lower limb strength, though the existing evidence remains inconsistent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the impact of PRT on lower limb muscle strength in youth with CP, compared to control or alternative interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study systematically reviewed randomized controlled trials (RCTs) following PRISMA guidelines. Six RCTs involving 232 participants with CP (ages 8\u201325 years, GMFCS levels I-III) were included in the quantitative meta-analysis. Standardized mean differences (Hedges\u2019 g) were calculated using a random-effects model. Risk of bias was assessed using the Cochrane RoB 2 tool, and evidence certainty was evaluated using GRADE framework.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      PRT significantly improved lower limb muscle strength compared to controls (Hedges\u2019 g\u2009=\u20090.46, 95% CI [0.26-0.66], p\u2009&lt;\u20090.001) with low-to-moderate heterogeneity (I\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200925.6%). Evidence certainty was rated as MODERATE. Subgroup analyses suggested potentially larger effects for gym-based interventions and participants with GMFCS II-III. Sensitivity analyses confirmed result robustness. No serious adverse events were reported.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PRT effectively enhances lower limb strength in youth (8\u201325 years) with CP, particularly under structured, supervised conditions. Further research is needed to clarify its long-term functional and psychosocial benefits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10538127261428185","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T18:05:28Z","timestamp":1773252328000},"page":"1292-1305","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The effects of progressive resistance training on lower limb strength in adolescents with cerebral palsy: A systematic review and meta-analysis"],"prefix":"10.1177","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8515-910X","authenticated-orcid":false,"given":"Yu","family":"Fang","sequence":"first","affiliation":[{"name":"Department of Public Culture, Nanchang Health Vocational and Technical College, Nanchang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weimin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Faculty of Education, Nanchang Vocational University, Nanchang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Faculty of Sports and Health, East China Jiaotong University, Nanchang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengpeng","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Public Culture, Nanchang Health Vocational and Technical College, Nanchang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haolan","family":"Li","sequence":"additional","affiliation":[{"name":"Physical Education Group, Anhui Lvhai Vocational College of Business, Anhui, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonthaya","family":"Sriramatr","sequence":"additional","affiliation":[{"name":"Department of Sports Science, Faculty of Physical Education, Sports and Health, Srinakharinwirot University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,5]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-022-01961-7"},{"key":"e_1_3_3_3_2","article-title":"Comprehensive approach to children with cerebral palsy","volume":"95","author":"Cantero MJP","year":"2021","unstructured":"Cantero MJP, Medinilla EEM, Mart\u00ednez AC, et al. Comprehensive approach to children with cerebral palsy. Anales de Pediatr\u00eda (English Edition) 2021; 95: 276. e1\u2013e11.","journal-title":"Anales de Pediatr\u00eda (English Edition)"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S235165"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci12070859"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0277543"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgph.0003003"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61599-3"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3109\/09638288.2015.1055376"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/02692155211040199"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16224513"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2016.06.003"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20100356"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1080\/17518423.2023.2218905"},{"key":"e_1_3_3_15_2","first-page":"1046","article-title":"The effect of a functional progressive strength training program on mobility of ambulatory adolescents and young adults with cerebral palsy","volume":"4","author":"Nikolaos C","year":"2019","unstructured":"Nikolaos C, Emmanouil S, Eirini G, et al. The effect of a functional progressive strength training program on mobility of ambulatory adolescents and young adults with cerebral palsy. 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