{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:57:39Z","timestamp":1790927859397,"version":"4.1.0"},"reference-count":40,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Back and Musculoskeletal Rehabilitation"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>No previous systematic reviews have evaluated the effects of blood flow restriction therapy (BFRT) in addition to other therapeutic interventions on clinical outcomes in patients with distal radius fractures (DRFs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine the clinical effects of BFRT on functional outcomes in patients with DRFs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An electronic search was performed using the MEDLINE, CENTRAL, EMBASE, Web of Science, PEDro, CINAHL, SPORTDiscus, and LILACS databases. The eligibility criteria included randomized clinical trials (RCTs) investigating the effects of BFRT with or without other therapeutic interventions on functional outcomes in patients with DRFs. Two authors independently performed the searches, study selection, data extraction, and risk of bias assessment using the Cochrane Risk of Bias 2.0. Data were pooled using a Hartung-Knapp-Sidik-Jonkman random-effects method or Mantel\u2013Haenszel fixed-effects model. Certainty of evidence was assessed using GRADE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Four RCTs met the eligibility criteria. For the comparison of BFRT plus standard rehabilitation versus standard rehabilitation alone, at four weeks and six to eight weeks, the overall mean difference (MD) for PRWE was \u22125.41 points (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.39), DASH was 1.94 points (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.84), grip strength was \u22122.47% (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.66), pinch strength was 0.28\u2005kg (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.59), wrist flexion-extension range of motion was 4.30 degrees (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.33), and VAS was 0.43\u2005cm (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.09).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Given the limited available evidence, the effectiveness of adding BFRT to standard rehabilitation remains uncertain. Preliminary findings suggest that BFRT did not improve any of the functional outcomes. More clinical trials, in both quantity and quality, are needed to confirm the clinical effects of BFRT in patients with DRFs.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>PROSPERO registration:<\/jats:bold>\n                      CRD42021260589.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10538127261489858","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T14:59:44Z","timestamp":1790607584000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of blood flow restriction therapy on functional outcomes in patients with distal radius fracture: A systematic review with meta-analysis"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4650-3426","authenticated-orcid":false,"given":"H\u00e9ctor","family":"Guti\u00e9rrez-Espinoza","sequence":"first","affiliation":[{"name":"Faculty of Education, Universidad Aut\u00f3noma de Chile, Santiago, Chile"},{"name":"Universidad Esp\u00edritu Santo, Samborond\u00f3n, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iv\u00e1n","family":"Cuy\u00fal-V\u00e1squez","sequence":"additional","affiliation":[{"name":"Departamento de Procesos Terap\u00e9uticos, Facultad de Ciencias de la Salud, Universidad Cat\u00f3lica de Temuco, Temuco, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Valenzuela-Fuenzalida","sequence":"additional","affiliation":[{"name":"Universidad Andres Bello"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Ponce-Fuentes","sequence":"additional","affiliation":[{"name":"Universidad Mayor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Rom\u00e1n-Veas","sequence":"additional","affiliation":[{"name":"Clinica Indisa, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Araya-Quintanilla","sequence":"additional","affiliation":[{"name":"Escuela de Kinesiolog\u00eda, Facultad de Ciencias de la Rehabilitaci\u00f3n y Calidad de Vida, Universidad San Sebasti\u00e1n, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jht.2016.03.003"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph20043697"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rifk.2011.09.001"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.physio.2012.09.003"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jht.2017.02.001"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.2009.02003.x"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3181915670"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0000000000000958"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/pzab022"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2015.5129"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2016-097071"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2019.00533"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-014-0288-1"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0000000000002384"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/pzab230"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.01269"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjpt.2020.03.001"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1685455"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/02692155211003480"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2023.2240329"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1712504"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000003228"},{"key":"e_1_3_3_24_2","volume-title":"Cochrane handbook for systematic reviews of interventions Version 6.3 [Updated February 2022]","author":"Higgins JPT","year":"2022","unstructured":"Higgins JPT, Thomas J, Chandler J, et al. 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