{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T13:32:10Z","timestamp":1793367130222,"version":"4.5.0"},"reference-count":50,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T00:00:00Z","timestamp":1744675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"European Union \u2013 NextGenerationEU","award":["ECS_00000035"],"award-info":[{"award-number":["ECS_00000035"]}],"id":[{"id":"https:\/\/ror.org\/019w4f821","id-type":"ROR","asserted-by":"crossref"}]},{"name":"European Union \u2013 NextGenerationEU","award":["PNRR-POC-2022-12375689"],"award-info":[{"award-number":["PNRR-POC-2022-12375689"]}],"id":[{"id":"https:\/\/ror.org\/019w4f821","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["NeuroRehabilitation"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Task-oriented training (TOT) is a commonly used intervention to improve upper extremity function after stroke. However, predictors of response to rehabilitation for performance and participation remain poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To identify baseline predictors of clinically significant upper extremity (UE) recovery across impairment, performance, and participation in individuals post-stroke following TOT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a retrospective study. Sixty-four individuals with stroke were enrolled and received five weeks of inpatient TOT for UE. Baseline characteristics and outcome measures were assessed using the Fugl-Meyer Assessment-Upper Extremity (FMA-UE) for impairment, the Action Research Arm Test (ARAT-15) for performance, and the QuickDASH-9 for participation. Participants were classified as responders and non-responders to the intervention, and binary logistic regression models were developed to predict responsiveness to impairment, performance, and participation measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All outcome measures showed significant improvement post-intervention. The baseline FMA-UE score, chronicity, and dominance of the involved UE predicted responsiveness for impairment. The FMA-UE score was the main predictor of responsiveness in performance, while no predictors were identified for participation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TOT improved UE impairment and performance in stroke patients, particularly those with moderate baseline impairment. Baseline UE function, chronicity, and dominance were key predictors of responsiveness in impairment and performance.<\/jats:p>\n                    <jats:p>This study highlights the importance of personalized TOT after a stroke. It demonstrates that baseline function, chronicity, and affected limb dominance predict impairment and performance responsiveness to TOT while emphasizing the need to incorporate strategies that facilitate real-world skill transfer and address personal and environmental factors to maximize participation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10538135251327090","type":"journal-article","created":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T13:44:50Z","timestamp":1744724690000},"page":"469-479","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors Associated with Clinical Meaningful Recovery after Upper Limb Task-Oriented Training in People with Stroke: A Cohort Study"],"prefix":"10.1177","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9774-2964","authenticated-orcid":false,"given":"Alberto","family":"Romano","sequence":"first","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6389-7379","authenticated-orcid":false,"given":"Anna","family":"Di Meo","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7797-2399","authenticated-orcid":false,"given":"Maurizio","family":"Ferrarin","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1990-8839","authenticated-orcid":false,"given":"Rune","family":"Thorsen","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4251-1856","authenticated-orcid":false,"given":"Davide","family":"Cattaneo","sequence":"additional","affiliation":[{"name":"Department of Pathophysiology and Transplantation, Universit\u00e0 degli Studi di Milano, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9533-5716","authenticated-orcid":false,"given":"Rita","family":"Bertoni","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8287-4881","authenticated-orcid":false,"given":"Johanna","family":"Jonsdottir","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,4,15]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/2516608519864760"},{"issue":"2","key":"e_1_3_4_3_1","article-title":"Rehabilitation of upper limb motor impairment in stroke: A narrative review on the prevalence, risk factors, and economic statistics of stroke and state of the art therapies","volume":"10","author":"Anwer S.","year":"2022","unstructured":"Anwer S., Waris A., Gilani S. O., Iqbal J., Shaikh N., Pujari A. N., Niazi I. K. (2022). Rehabilitation of upper limb motor impairment in stroke: A narrative review on the prevalence, risk factors, and economic statistics of stroke and state of the art therapies. Healthcare (Switzerland), 10(2), 190. https:\/\/doi.org\/10.3390\/healthcare10020190","journal-title":"Healthcare (Switzerland)"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638280500075717"},{"issue":"8","key":"e_1_3_4_5_1","article-title":"Action observation for upper limb rehabilitation after stroke","volume":"2022","author":"Borges L. R. D. M.","year":"2022","unstructured":"Borges L. R. D. M., Fernandes A. B. G. S., Oliveira dos Passos J., Rego I. A. O., Campos T. F. (2022). Action observation for upper limb rehabilitation after stroke. 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