{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T20:48:48Z","timestamp":1782074928655,"version":"3.54.5"},"reference-count":35,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52305035"],"award-info":[{"award-number":["52305035"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62436005"],"award-info":[{"award-number":["62436005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Qinchuangyuan (Shaanxi) \u201cScientist + Engineer\u201d Team Building Program","award":["2022KXJ-055"],"award-info":[{"award-number":["2022KXJ-055"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["NeuroRehabilitation"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To systematically characterize the cortical dynamics underlying fine hand motor impairment in patients with acute ischemic stroke (AIS) using a multidimensional task-state electroencephalography (EEG) analysis framework.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Fifteen patients with AIS and sixteen age- and sex-matched healthy controls were enrolled. EEG signals were recorded while participants performed three standardized fine motor tasks, including fist clenching, index finger pointing, and thumb-finger opposition. Source localization, time-frequency analysis, and brain network topology analysis were jointly applied to extract multidimensional electrophysiological features. Correlation analyses were further conducted to examine the relationships between EEG-derived metrics and clinical measures, including muscle strength grading, National Institutes of Health Stroke Scale (NIHSS) scores, and Activities of Daily Living (ADL) scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with healthy controls, patients with AIS showed abnormal spatiotemporal cortical dynamics during fine hand movements. These abnormalities included delayed movement-related potentials, a shift of alpha- and beta-band event-related desynchronization from contralateral dominance toward more bilateral and diffuse activation, and altered brain network organization characterized by reduced network efficiency and changes in nodal centrality. In addition, EEG-derived features were significantly associated with clinical measures. Specifically, several event-related desynchronization\/event-related synchronization (ERD\/ERS)-related amplitudes and small-world properties were significantly correlated with muscle strength grading, NIHSS scores, and ADL scores after false discovery rate correction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Multidimensional task-state EEG analysis can characterize cortical activation abnormalities and network reorganization associated with fine hand motor impairment in patients with AIS. The identified EEG-derived metrics may serve as objective markers for post-stroke motor function assessment and recovery monitoring, and may help support individualized rehabilitation evaluation and planning.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10538135261441843","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:37:06Z","timestamp":1777466226000},"page":"636-650","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Task-State EEG Reveals Fine Hand Motor Impairment in Acute Ischemic Stroke: A Multidimensional Analysis of Cortical Dynamics"],"prefix":"10.1177","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8799-3729","authenticated-orcid":false,"given":"Ke","family":"Deng","sequence":"first","affiliation":[{"name":"Postgraduate Office, Xi'an Medical University, Xi'an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of General Practice, Yuxi Town Branch, Bazhong Enyang District General Hospital, Bazhong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqi","family":"Liu","sequence":"additional","affiliation":[{"name":"Postgraduate Office, Xi'an Medical University, Xi'an, China"},{"name":"Department of Brain, Xi\u2019an People's Hospital (Xi\u2019an Fourth Hospital), Xi'an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chune","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Brain, Xi\u2019an People's Hospital (Xi\u2019an Fourth Hospital), Xi'an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofei","family":"Lin","sequence":"additional","affiliation":[{"name":"Postgraduate Office, Xi'an Medical University, Xi'an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqing","family":"Wei","sequence":"additional","affiliation":[{"name":"School of Mechanical and Precision Instruments, Xi'an University of Technology, Xi'an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Li","sequence":"additional","affiliation":[{"name":"School of Mechanical and Precision Instruments, Xi'an University of Technology, Xi'an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiping","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Brain, Xi\u2019an People's Hospital (Xi\u2019an Fourth Hospital), Xi'an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12984-023-01223-7"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1747493017711816"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1425-23.2023"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2024.12.016"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.25297"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2021.632237"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.124.048458"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.031313"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-024-09597-0"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2022.935827"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12984-022-01072-w"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-022-00959-x"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/15459683241230029"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41386-019-0468-7"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2023.1151852"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.23713"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.4235\/agmr.24.0172"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/ad9403"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2020.00827"},{"key":"e_1_3_2_21_1","article-title":"Sensorimotor rhythm-brain computer interface with audio-cue, motor observation and multisensory feedback for upper-limb stroke rehabilitation: A controlled study","volume":"16","author":"Li X.","year":"2022","unstructured":"Li X., Wang L., Miao S., Yue Z., Tang Z., Su L., Zheng Y., Wu X., Wang S., Wang J., Dou Z. 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