{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T16:19:11Z","timestamp":1787933951791,"version":"build-2784847793"},"reference-count":65,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["NeuroRehabilitation"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Gait variability is a sensitive marker of neuromotor function and a clinically relevant indicator of fall risk and mobility impairment in neurological and geriatric populations. The Enhanced Gait Variability Index (eGVI) has emerged as a promising composite measure that captures multidimensional gait irregularity in a single interpretable score, offering a practical advantage over single-parameter approaches. Despite growing clinical interest, the evidence base supporting its standardized implementation has not been mapped.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To characterize populations and clinical contexts where the eGVI has been applied, map assessment protocol heterogeneity, and identify methodological gaps limiting precision medicine-aligned implementation in neurological and geriatric rehabilitation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A scoping review following PRISMA-ScR guidelines was conducted using PubMed, CINAHL, Scopus, Emcare, and Web of Science. Peer-reviewed studies reporting eGVI outcomes were included. Data were extracted on participant characteristics, gait assessment protocols, and outcomes, with attention to factors influencing clinical interpretation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighteen studies involving 1,915 participants were included, predominantly examining Parkinson's disease (39%) and older adult populations (22%). The eGVI demonstrated preliminary sensitivity to neuromotor impairment, age-related gait changes, and increased task complexity during dual-task walking; findings were most consistent in Parkinson's disease, based on limited number of studies (n\u2009=\u20097). Substantial heterogeneity in walkway systems, walking conditions, assistive device use, and reference populations limited comparability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>While the eGVI shows promise as a clinical outcome measure, protocol variability and reliance on a single unvalidated normative reference limit its clinical use. Population-specific protocols and normative data consistent with a precision medicine approach, are essential for reliable adoption.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10538135261465012","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T08:50:30Z","timestamp":1783500630000},"page":"200-217","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Enhanced Gait Variability Index in Neurological and Geriatric Rehabilitation: A Scoping Review"],"prefix":"10.1177","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2081-3996","authenticated-orcid":false,"given":"Mengdi","family":"Wang","sequence":"first","affiliation":[{"name":"School of Physical Therapy, Texas Woman's University, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8483-8086","authenticated-orcid":false,"given":"Priya","family":"Karakkattil","sequence":"additional","affiliation":[{"name":"School of Physical Therapy, Texas Woman's University, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,8]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/app142311321"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2008.10.061"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02612.x"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofab425"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-6362(02)00053-X"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsos.171673"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/17483107.2011.602461"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.26603\/001c.142435"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcomdis.2025.106615"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2025.07.323"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000500413"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12984-016-0154-5"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-6362(01)00101-1"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0141694"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2015.05.019"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2012.09.022"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-020-09725-3"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2019.08.005"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2013.01.013"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0198267"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-0003-2-19"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/10400435.2023.2239555"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s11556-019-0214-5"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-39718-w"},{"issue":"4","key":"e_1_3_3_26_1","article-title":"Enhanced gait variability Index in older Asian adults and increased physiological fall risk: Results from the yishun study","volume":"2","author":"Jabbar K. 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