{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:44:43Z","timestamp":1792075483179,"version":"4.4.0"},"reference-count":36,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["NeuroRehabilitation"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Stroke affects physical, psychological, and social functioning. Early changes in health-related quality of life (HRQoL) remain incompletely characterized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess early HRQoL changes after stroke and identify associated factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We assessed 111 patients with first-ever stroke at baseline, 1 month, and 3 months. Functional status, cognition, depressive symptoms, and HRQoL were evaluated using the Barthel Index, Functional Ambulation Scale, Mini-Mental State Examination, Beck Depression Inventory, Form-36 (SF-36) and the Stroke Impact Scale 3.0 (SIS 3.0). Paired tests, correlations with false discovery rate correction, and multivariable linear regression were used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ninety-seven patients completed follow-up. Physical and psychosocial HRQoL showed divergent recovery trajectories. SF-36 physical component scores progressively improved across both intervals (baseline to 1 month,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009\u2009=\u2009\u20090.006; 1 to 3 months,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.033), whereas mental component scores improved only during the first month (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.021) and showed no further significant improvement thereafter (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.342). Similarly, SIS 3.0 emotion scores showed no significant change between 1 and 3 months (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.831) and no significant net change over 3 months (\n                      <jats:italic toggle=\"yes\">q<\/jats:italic>\n                      \u2009=\u20090.103), unlike the other domains, which continued to improve. In multivariable regression, functional ambulation at 3 months was independently associated with physical HRQoL change (\u03b2\u2009=\u20090.483,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001; adjusted R\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.450), whereas depressive symptom severity was independently associated with mental HRQoL change (\u03b2\u2009=\u2009\u22120.692,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001; adjusted R\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.667).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Physical and psychosocial HRQoL did not recover in parallel during the first 3 months after stroke. Ambulation and depressive symptoms warrant separate attention during early rehabilitation planning.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10538135261494069","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:13:42Z","timestamp":1791868422000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Early Changes in Post-Stroke Quality of Life and Associated Factors: A Prospective Study"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9375-2003","authenticated-orcid":false,"given":"Senay","family":"Demir Yazici","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Trakya University Faculty of Medicine, Edirne, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Birtane","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Trakya University Faculty of Medicine, Edirne, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nurettin","family":"Tastekin","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Trakya University Faculty of Medicine, Edirne, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galip","family":"Ekuklu","sequence":"additional","affiliation":[{"name":"Department of Public Health, Trakya University Faculty of Medicine, Edirne, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ufuk","family":"Utku","sequence":"additional","affiliation":[{"name":"Department of Neurology, Trakya University Faculty of Medicine, Edirne, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilda","family":"Turgut","sequence":"additional","affiliation":[{"name":"Department of Neurology, Trakya University Faculty of Medicine, Edirne, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talip","family":"Asil","sequence":"additional","affiliation":[{"name":"Department of Neurology, Trakya University Faculty of Medicine, Edirne, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"issue":"2","key":"e_1_3_3_2_1","first-page":"89","article-title":"Factors associated with health-related quality of life of patients with stroke","volume":"27","author":"A\u011f\u0131r H.","year":"2024","unstructured":"A\u011f\u0131r H. (2024). Factors associated with health-related quality of life of patients with stroke. Journal of Physical Medicine and Rehabilitation, 27(2), 89\u201395. https:\/\/doi.org\/10.31609\/jpmrs.2023-96197","journal-title":"Journal of Physical Medicine and Rehabilitation"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/22799036231204321"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.2478\/sjph-2022-0014"},{"key":"e_1_3_3_5_1","doi-asserted-by":"crossref","unstructured":"Beck A. T. Steer R. A. Brown G. K. (1996). Beck depression inventory.","DOI":"10.1037\/t00742-000"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/31.6.451"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/67.2.206"},{"key":"e_1_3_3_8_1","unstructured":"Brunnstrom S. (1970). Movement therapy in hemiplegia. 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