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Using a sample of 231 women, multiple and moderate mediation analyses were conducted with PROCESS. Results showed that depression was positively associated with activity avoidance and excessive persistence. Furthermore, cognitive fusion and pain acceptance were found to mediate the effect of depression in both patterns. Additionally, pain acceptance was found to play a contextual role in cognitive fusion, as a moderator, between depressive symptoms and maladaptive patterns. Specifically, FM patients with high acceptance levels and low levels of depression presented the strongest associations between depression and cognitive fusion. Techniques aimed at reducing cognitive fusion, could be especially beneficial to FM women with high pain acceptance.<\/jats:p>","DOI":"10.1177\/10547738211034307","type":"journal-article","created":{"date-parts":[[2021,7,24]],"date-time":"2021-07-24T01:23:30Z","timestamp":1627089810000},"page":"217-229","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["What Does the Psychological Flexibility Model Contribute to the Relationship Between Depression and Disability in Chronic Pain? 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