{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:22:55Z","timestamp":1777522975321,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2018,5,23]],"date-time":"2018-05-23T00:00:00Z","timestamp":1527033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To determine the safety of ibuprofen used for postoperative pain control following palatoplasty in pediatric patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Retrospective chart review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Tertiary care, pediatric hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>Patients who received ibuprofen for postoperative pain control after palatoplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures:<\/jats:title>\n                    <jats:p>Number of doses of ibuprofen given during hospitalization and the presence of postoperative primary or secondary bleeding following palatoplasty. Detection of postoperative hemorrhage was obtained from (1) chart review from inpatient hospitalization after palatoplasty, (2) chart review of each patient\u2019s 3-week postoperative clinic visit, and (3) phone call to caretakers from primary author.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Thirty-two patients underwent palatoplasty who received ibuprofen for control of postoperative pain. Mean number of inpatient doses given was 4.8 (range: 1-17). None (0%) experienced hemorrhage in the hospital before discharge. Thirty-two (100%) patients were seen at a 3-week follow-up and no (0%) episodes of postoperative hemorrhage were noted. Seventeen (53%) caretakers of patients responded to contact by phone and confirmed no subsequent bleeding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Ibuprofen may not increase postoperative hemorrhage after palatoplasty. Further studies will be needed to evaluate safety on a larger scale.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665618760532","type":"journal-article","created":{"date-parts":[[2018,5,23]],"date-time":"2018-05-23T14:48:50Z","timestamp":1527086930000},"page":"1130-1132","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Safety of Ibuprofen for Postoperative Pain After Palatoplasty"],"prefix":"10.1177","volume":"55","author":[{"given":"Brandon R.","family":"Cardon","sequence":"first","affiliation":[{"name":"College of Medicine, Oklahoma University, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael P.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology, College of Public Health, Oklahoma University, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S.","family":"Glade","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Oklahoma State University, Tulsa, OK, USA"},{"name":"Department of Oral and Maxillofacial Surgery, Oklahoma University, Oklahoma City, OK, USA"},{"name":"Pediatric ENT of Oklahoma, Oklahoma City, Oklahoma, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,5,23]]},"reference":[{"issue":"6","key":"bibr1-1055665618760532","first-page":"S118","volume":"94","author":"Augsomwan D","year":"2011","journal-title":"J Med Assoc Thai"},{"key":"bibr2-1055665618760532","first-page":"CD0003591","volume":"18","author":"Cardwell M","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr3-1055665618760532","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2007.11"},{"key":"bibr4-1055665618760532","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.10.1086"},{"key":"bibr5-1055665618760532","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-200301000-00015"},{"key":"bibr6-1055665618760532","unstructured":"Nierengarten MB. Post-operative pain in children undergoing tonsillectomy. ENT Today. 9 2012. Available at: http:\/\/www.enttoday.org\/details\/article\/2544431\/Post-Operative_Pain_in_Children_Undergoing_Tonsillectomy.html. Accessed March 25, 2014."},{"key":"bibr7-1055665618760532","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/88.1.72"},{"key":"bibr8-1055665618760532","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2013.40.3.263"},{"key":"bibr9-1055665618760532","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2012.01419.x"},{"key":"bibr10-1055665618760532","unstructured":"US Food and Drug Administration. FDA Drug Safety Communication: codeine use in certain children after tonsillectomy and\/or adenoidectomy may lead to rare, but life-threatening adverse events or death. Available at: http:\/\/www.fda.gov\/Drugs\/DrugSafety\/ucm313631.htm#caregivers. Accessed July 29, 2013."},{"key":"bibr11-1055665618760532","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-010-1393-x"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665618760532","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1055665618760532","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665618760532","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:19:10Z","timestamp":1777393150000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1055665618760532"}},"subtitle":["A Pilot Study"],"short-title":[],"issued":{"date-parts":[[2018,5,23]]},"references-count":11,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1177\/1055665618760532"],"URL":"https:\/\/doi.org\/10.1177\/1055665618760532","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,23]]}}}