{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:04:49Z","timestamp":1790114689695,"version":"4.0.1"},"reference-count":64,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T00:00:00Z","timestamp":1520985600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate-Craniofacial Journal"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To investigate the structural and intermediary determinants of health-related quality of life (HRQoL) and oral health\u2013related quality of life (OHRQoL) among adults with cleft lip and\/or palate (CL\/P).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design and Participants:<\/jats:title>\n                    <jats:p>A cross-sectional study was conducted with patients enrolled at the referral center for craniofacial anomalies in Manaus, Brazil. Adults aged 18 years or more with nonsyndromic CL\/P were selected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures:<\/jats:title>\n                    <jats:p>Both HRQoL and OHRQoL were assessed using the 36-item Short-Form Health Survey and the Oral Impacts on Daily Performance, respectively. Individual interviews and oral examinations were conducted to collect data on socioeconomic and demographic characteristics, social ties, health-related behaviors, compliance of CL\/P protocol, chronic diseases, type of CL\/P, oral clinical measures, and CL\/P-related measures. Poisson regression was used to test the association of independent variables with HRQoL and OHRQoL outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean age of the 96 participants was 29.4 \u00b1 9.1 years. Low family income, female sex, low social support, type of CL\/P, and dental caries were associated with poor HRQoL and poor OHRQoL ( P &lt; .05). Poor HRQoL was also associated with chronic diseases ( P &lt; .05). Adults with low education, low social network, and smokers were more likely to have worse OHRQoL ( P &lt; .05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Structural and intermediary determinants were related to HRQoL and OHRQoL in adults with CL\/P, suggesting the need for interdisciplinary approaches to improve the management of CL\/P and intersectoral actions to reduce the impact of social inequalities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665618763377","type":"journal-article","created":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T12:29:28Z","timestamp":1521030568000},"page":"1244-1257","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Determinants of Health-Related and Oral Health\u2013Related Quality of Life in Adults With Orofacial Clefts"],"prefix":"10.1177","volume":"55","author":[{"given":"Ana Paula","family":"Corr\u00eaa de Queiroz Herkrath","sequence":"first","affiliation":[{"name":"School of Dentistry, Federal University of Amazonas, Manaus, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando Jos\u00e9","family":"Herkrath","sequence":"additional","affiliation":[{"name":"State University of Amazonas, Manaus, Brazil"},{"name":"Instituto Le\u00f4nidas e Maria Deane, Funda\u00e7\u00e3o Oswaldo Cruz, Manaus, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Augusta","family":"Bessa Rebelo","sequence":"additional","affiliation":[{"name":"School of Dentistry, Federal University of Amazonas, Manaus, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario Vianna","family":"Vettore","sequence":"additional","affiliation":[{"name":"Academic Unit of Oral Health, Dentistry and Society, University of Sheffield, Sheffield, United 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