{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:23:36Z","timestamp":1777523016454,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,4,30]],"date-time":"2018-04-30T00:00:00Z","timestamp":1525046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>This report describes the presentation of a newborn male with circumferential tongue-palate fusion associated with cleft palate and alveolar bands. After intraoral adhesions lysis, the patient was diagnosed with Pierre Robin sequence. A family history of cleft lip and palate was noted, and interferon regulatory factor 6 ( IRF6) sequencing revealed a heterozygous variant, confirming the diagnosis of van der Woude syndrome. The disruption of IRF6 resulted in abnormal orofacial development including micrognathia and intraoral adhesions as well as tongue-palate fusion, then resulting in glossoptosis with airway obstruction and cleft palate.<\/jats:p>","DOI":"10.1177\/1055665618773192","type":"journal-article","created":{"date-parts":[[2018,4,30]],"date-time":"2018-04-30T14:22:03Z","timestamp":1525098123000},"page":"123-126","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Combined Tongue-Palate Fusion With Alveolar Bands in a Patient With Pierre Robin Sequence and Van der Woude Syndrome"],"prefix":"10.1177","volume":"56","author":[{"given":"Alexa","family":"Robbins","sequence":"first","affiliation":[{"name":"College of Medicine, The University of Arkansas for Medical Sciences, Little Rock, AR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuri A.","family":"Zarate","sequence":"additional","affiliation":[{"name":"Section of Genetics and Metabolism, The University of Arkansas for Medical Sciences, Little Rock, AR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larry D.","family":"Hartzell","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, The University of Arkansas for Medical Sciences, Little Rock, AR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,4,30]]},"reference":[{"key":"bibr1-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.37791"},{"key":"bibr2-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200110000-00028"},{"key":"bibr3-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1097\/GIM.0b013e318197a49a"},{"key":"bibr4-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2002_039_0115_npjcbo_2.0.co_2"},{"key":"bibr5-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2016.11.012"},{"key":"bibr6-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1320065"},{"key":"bibr7-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31824de3bf"},{"key":"bibr8-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1177\/000348949310200305"},{"key":"bibr9-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2003.009274"},{"key":"bibr10-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1038\/ng1903"},{"key":"bibr11-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.10048"},{"key":"bibr12-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.12.016"},{"key":"bibr13-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2016.09.023"},{"key":"bibr14-1055665618773192","doi-asserted-by":"publisher","DOI":"10.4103\/2231-0746.161102"},{"key":"bibr15-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2013.11.009"},{"key":"bibr16-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-011-0244-7"},{"key":"bibr17-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp201"},{"key":"bibr18-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1038\/ng1894"},{"key":"bibr19-1055665618773192","doi-asserted-by":"publisher","DOI":"10.4103\/0970-0358.182238"},{"key":"bibr20-1055665618773192","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.01.021"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665618773192","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1055665618773192","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665618773192","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:19:20Z","timestamp":1777393160000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1055665618773192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,30]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1177\/1055665618773192"],"URL":"https:\/\/doi.org\/10.1177\/1055665618773192","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,30]]}}}