{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T21:33:08Z","timestamp":1793741588815,"version":"4.6.1"},"reference-count":59,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,5,18]],"date-time":"2018-05-18T00:00:00Z","timestamp":1526601600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To estimate the prevalence of symptoms of obstructive sleep apnea (OSA), nasal obstruction, and enuresis in children with nonsyndromic unilateral cleft lip and palate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Prospective cross-sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Referral care center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>One hundred seventy-four children aged 6 to 12 years of both genders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions:<\/jats:title>\n                    <jats:p>Symptoms of OSA and nasal obstruction were investigated by analysis of scores obtained by the Sleep Disturbance Scale for Children (SDSC) and Congestion Quantifier (CQ-5). Enuresis was considered as present when urinary loss was reported during sleep (at least 1 episode\/month, last 3 months). To characterize the enuresis as mono- or polysymptomatic, symptoms of dysfunction of the lower urinary tract (DLUT) were investigated by the Dysfunctional Voiding Scoring System (DVSS). Statistical analysis was performed at a 5% level of significance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Positive SDSC scores for OSA were observed in 60 (34%) children; positive CQ-5 scores for nasal obstruction in 45 (26%), positive DVSS scores for DLUT in 30 (17%), and enuresis was reported by 29 (17%), being categorized as primary in 66% and polysymptomatic in 72% of the children. Compared to the pediatric population, OSA, nasal obstruction, and enuresis prevalence ratios were up to 7 (95% confidence interval [CI] 5-9), 2 (95% CI 2-3), and 3 times (95% CI 2-5) higher, respectively. There was a positive\/moderate correlation between symptoms of OSA and nasal obstruction (\n                      <jats:italic>P<\/jats:italic>\n                      = .0001). No correlation was seen between symptoms of OSA and enuresis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Children with nonsyndromic cleft lip and palate have high prevalence of nasal obstruction and enuresis and are at risk of OSA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665618776074","type":"journal-article","created":{"date-parts":[[2018,5,18]],"date-time":"2018-05-18T19:10:11Z","timestamp":1526670611000},"page":"307-313","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Symptoms of Obstructive Sleep Apnea, Nasal Obstruction, and Enuresis in Children With Nonsyndromic Cleft Lip and Palate: A Prevalence Study"],"prefix":"10.1177","volume":"56","author":[{"given":"Marilyse de Bragan\u00e7a Lopes","family":"Fernandes","sequence":"first","affiliation":[{"name":"Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of Sao Paulo, Bauru-SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Al\u00edcia Graziela Noronha Silva","family":"Salgueiro","sequence":"additional","affiliation":[{"name":"Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of Sao Paulo, Bauru-SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliete Jana\u00edna Bueno","family":"Bighetti","sequence":"additional","affiliation":[{"name":"Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of Sao Paulo, Bauru-SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivy Kiemle","family":"Trindade-Suedam","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Bauru School of Dentistry and Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of Sao Paulo, Bauru-SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inge Elly Kiemle","family":"Trindade","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Bauru School of Dentistry and Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of Sao Paulo, Bauru-SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,5,18]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20697"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2006.02.021"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2012.02791.x"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.01.110"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2805"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.04.017"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.2172"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/32.6.731"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2003.027011"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2869.1996.00251.x"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365590701748054"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1677-55382010000400009"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2013.05.011"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(99)00009-X"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000000484"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/34.2.191"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.05.103"},{"key":"e_1_3_2_19_1","first-page":"437","article-title":"Primary nocturnal enuresis as a risk factor for sleep disorders: an observational questionnaire-based multicenter study","volume":"9","author":"Esposito M","year":"2013","unstructured":"Esposito M, Gallai B, Parisi L, Roccella M, Marotta R, Lavano SM, Mazzotta G, Carotenuto M. 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