{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T11:43:46Z","timestamp":1791632626191,"version":"4.3.4"},"reference-count":43,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,5,25]],"date-time":"2018-05-25T00:00:00Z","timestamp":1527206400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Marmara \u00dcniversitesi Scientific Research Committee","award":["SAG-A-040609-0165"],"award-info":[{"award-number":["SAG-A-040609-0165"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The aim of this study was to examine the microbiological changes in newborn babies with cleft lip palate from birth up to age 3 and to correlate them with their caries levels and mothers\u2019 microbiological data and to compare with normal infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Basic Research Design:<\/jats:title>\n                    <jats:p>Prospective.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Settings:<\/jats:title>\n                    <jats:p>Marmara University, Faculty of Dentistry, Pediatric Dentistry Clinic, and \u015ei\u015fli Hamidiye Etfal Education and Research Hospital New Born Clinic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients\/Participants:<\/jats:title>\n                    <jats:p>Cleft lip palate (n = 21) and healthy (n = 13) newborns and their mothers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods:<\/jats:title>\n                    <jats:p>Intraoral samples were taken from babies in each group at least 3 times over the 3 years. Saliva samples of the mothers were collected just after the birth of the babies and examined microbiologically. Dental caries was noted as either present or absent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The most frequent microorganisms were candida, found at birth (n = 9, 42%) in cleft palate with or without cleft lip (CP\u00b1L) group. The number of babies infected with\n                      <jats:italic>Lactobacilli<\/jats:italic>\n                      were found to be significantly higher in the CP\u00b1L group than in the control group at birth (\n                      <jats:italic>P<\/jats:italic>\n                      = .029) and after eruption of the first primary tooth (\n                      <jats:italic>P<\/jats:italic>\n                      = .030).\n                      <jats:italic>Mutans Streptococci<\/jats:italic>\n                      were found in 10% of babies with CP\u00b1L at birth. Initial caries was identified in 20% of the babies with an oral cleft compared with 0% of the controls after eruption of the first primary incisors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The results show that the CP\u00b1L babies must be considered as a group with an increased caries risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665618776428","type":"journal-article","created":{"date-parts":[[2018,5,25]],"date-time":"2018-05-25T17:37:36Z","timestamp":1527269856000},"page":"349-356","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["Microbial Profile and Dental Caries in Cleft Lip and Palate Babies Between 0 and 3 Years Old"],"prefix":"10.1177","volume":"56","author":[{"given":"M\u00fcesser Ahu","family":"Durhan","sequence":"first","affiliation":[{"name":"Department of Paediatric Dentistry, Faculty of Dentistry, Marmara University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nursen","family":"Topcuoglu","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guven","family":"Kulekci","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ege","family":"Ozgentas","sequence":"additional","affiliation":[{"name":"Private Practice, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilknur","family":"Tanboga","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry, Faculty of Dentistry, Marmara University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,5,25]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1597\/04-083r.1"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.1996.tb00135.x"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1996_033_0424_posmal_2.3.co_2"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03262754"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0000000000000305"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345930720010501"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2001_038_0525_tohocw_2.0.co_2"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1597\/05-112"},{"issue":"2","key":"e_1_3_2_10_1","first-page":"130","article-title":"Association between early childhood caries and colonization with Streptococcus Mutans genotypes from mothers","volume":"39","author":"Childers NK","year":"2017","unstructured":"Childers NK, Momeni SS, Whiddon J, Cheon K, Cutter GR, Wiener HW, Ghazal TS, Ruby JD, Moser SA. 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