{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:14:35Z","timestamp":1780481675903,"version":"3.54.1"},"reference-count":38,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,6,20]],"date-time":"2018-06-20T00:00:00Z","timestamp":1529452800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the influence of cleft type and width, canine eruption stage, and surgeon on the outcomes of alveolar graft with rhBMP-2.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Cross-sectional.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Tertiary craniofacial center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>Ninety individuals submitted to alveolar graft in late mixed or early permanent dentition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions:<\/jats:title>\n                    <jats:p>The 90 individuals (mean age: 16.8 years) were submitted to alveolar graft with rhBMP-2. Periapical radiographs were obtained before and 6 months after surgery. Surgeries were performed by 4 experienced maxillofacial surgeons. The alveolar grafts were assigned as success or failure by 3 blinded raters based on the modified Bergland and Chelsea scales. Permanent canines adjacent to the defect were assigned as erupted and not erupted. The greatest cleft width was measured on preoperative periapical radiographs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures:<\/jats:title>\n                    <jats:p>\n                      The influence of 4 independent variables (cleft type, cleft width, canine eruption phase, and surgeon) on the outcome of alveolar graft was analyzed by multivariate logistic regression (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      All independent variables presented significant influence on alveolar graft outcome. The subgroup of unerupted maxillary canines demonstrated better outcomes than erupted canines (\n                      <jats:italic>P<\/jats:italic>\n                      = .001). The group with cleft lip and alveolus (CL\/A) demonstrated better outcomes than complete cleft lip and palate (CLP;\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001). The greater the alveolar cleft width, the less favorable were the graft outcomes (\n                      <jats:italic>P<\/jats:italic>\n                      = .027). The surgeon also had a significant influence on the surgery success (\n                      <jats:italic>P<\/jats:italic>\n                      = .003 and .001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The type and width of CLP, the eruption of permanent canines, and the surgeon influenced the outcome of alveolar graft surgeries performed with rhBMP-2.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665618780981","type":"journal-article","created":{"date-parts":[[2018,6,20]],"date-time":"2018-06-20T13:11:15Z","timestamp":1529500275000},"page":"383-389","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["Outcomes of Alveolar Graft With Rhbmp-2 in CLP: Influence of Cleft Type and Width, Canine Eruption, and Surgeon"],"prefix":"10.1177","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6430-612X","authenticated-orcid":false,"given":"Claudia Resende","family":"Leal","sequence":"first","affiliation":[{"name":"Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta Martinelli","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terumi Okada","family":"Ozawa","sequence":"additional","affiliation":[{"name":"Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Araci Malagodi","family":"de Almeida","sequence":"additional","affiliation":[{"name":"Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele","family":"da Silva Dalben","sequence":"additional","affiliation":[{"name":"Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Jos\u00e9 Carlos","family":"da Cunha Bastos","sequence":"additional","affiliation":[{"name":"Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela Gamba","family":"Garib","sequence":"additional","affiliation":[{"name":"Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,6,20]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844318109103425"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tec.2009.0824"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2000_036_0179_tpsota_2.3.co_2"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650081326"},{"issue":"3","key":"e_1_3_2_6_1","first-page":"175","article-title":"Elimination of the residual alveolar cleft by secondary bone grafting and subsequent orthodontic treatment","volume":"23","author":"Bergland O","year":"1986","unstructured":"Bergland O, Semb G, Abyholm FE. 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In: Buser D, Dahlin C, Schenk RK, eds. Regenera\u00e7\u00e3o \u00f3ssea guiada na implantodontia [in Portuguese]. S\u00e3o Paulo, Brazil: Quintessence Books; 1996:49\u2013100."},{"key":"e_1_3_2_28_1","unstructured":"Schwab J. Multinomial Logistic Basic. Relationships. http:\/\/www.utexas.edu\/courses\/schwab\/sw388r7\/SolvingProblems\/Analyzi. 2007."},{"issue":"3","key":"e_1_3_2_29_1","first-page":"288","article-title":"Effect of alveolar bone grafting on maxillary growth in unilateral cleft lip and palate patients","volume":"25","author":"Semb G","year":"1988","unstructured":"Semb G. Effect of alveolar bone grafting on maxillary growth in unilateral cleft lip and palate patients. 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