{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:26:47Z","timestamp":1777523207756,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,7,30]],"date-time":"2019-07-30T00:00:00Z","timestamp":1564444800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:p>\n                    Patients presenting with a unique unilateral cleft phenotype may be at risk of nasal airway obstruction which can be exacerbated by presurgical infant orthopedic (PSIO) appliance therapy and lip taping. Four patients presented to the UPMC Children\u2019s Hospital of Pittsburgh Cleft-Craniofacial Center with a cleft phenotype characterized by:\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>An anteriorly projected greater alveolar segment and medial collapse of the lesser segment posteriorly, leading to cleft alar base displacement posteromedial to the anteriorly projected greater segment.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Resultant bilateral nasal airway obstruction: cleft ala drape over the leading edge of the greater segment\u2019s alveolus (cleft side obstruction) and caudal septum displacement secondary to attachments to the orbicularis oris from the noncleft side (noncleft side obstruction).<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>\n                  <jats:p>The patient described presented at 3 months old from an outside institution, where PSIO therapy was undertaken. A second opinion was sought due to concern of significant difficulty in breathing and feeding with the PSIO oral plate. Lip-nose adhesion (LNA) was elected and airway obstruction was immediately relieved after this intervention. Lip-nose adhesion releases the tethered cleft side alar base from the pyriform rim of the posteromedially collapsed lesser segment and unites the superior lip and nostril sill\u2014relieving the cleft side nostril obstruction. During the LNA, the caudal septum is surgically released from the anterior nasal spine and is uprighted, relieving the obstructed noncleft nostril.<\/jats:p>\n                  <jats:p>In this cleft anatomy, the treatment alternatives of modification to the PSIO appliance or LNA should be carefully considered in consultation with the surgeon, PSIO provider, and the infant\u2019s caretakers.<\/jats:p>","DOI":"10.1177\/1055665619866354","type":"journal-article","created":{"date-parts":[[2019,7,31]],"date-time":"2019-07-31T00:05:32Z","timestamp":1564531532000},"page":"245-248","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Airway Obstruction Risk in Unique Infant Cleft Phenotype: PSIO Protocol Modification Recommendations"],"prefix":"10.1177","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7767-4666","authenticated-orcid":false,"given":"Aaron M.","family":"Foglio","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, Children\u2019s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan Y.","family":"Lee","sequence":"additional","affiliation":[{"name":"Baystate Plastic Surgery, Springfield, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Naran","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Children\u2019s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA"},{"name":"Division of Pediatric Plastic Surgery, Advocate Children\u2019s Hospital, Park Ridge, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsay A.","family":"Schuster","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Children\u2019s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Davit","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Children\u2019s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesse A.","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Children\u2019s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph E.","family":"Losee","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Children\u2019s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,7,30]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0000000000000737"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844310903569378"},{"key":"e_1_3_2_4_1","first-page":"701","article-title":"Nasoalveolar molding and columella elongation in preparation for the primary repair of unilateral and bilateral cleft lip and palate","author":"Grayson BH","year":"2009","unstructured":"Grayson BH, Garfinkle JS. Nasoalveolar molding and columella elongation in preparation for the primary repair of unilateral and bilateral cleft lip and palate. In: Losee JE, ed. Comprehensive Cleft Care. New York: McGraw-Hill; 2009:701\u2013720.","journal-title":"Comprehensive Cleft Care"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1597\/07-236.1"},{"issue":"10","key":"e_1_3_2_6_1","first-page":"S17","article-title":"Pre-surgical nasoalveolar molding technique: a literature review","volume":"97","author":"Manosudprasit M","year":"2014","unstructured":"Manosudprasit M, Wangsrimongkol T, Pisek P, Wiwatworakul O. Pre-surgical nasoalveolar molding technique: a literature review. J Med Assoc Thai. 2014;97(suppl 10):S17\u2013S24.","journal-title":"J Med Assoc Thai"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844317909013074"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/207605"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318267d4a5"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665619866354","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1055665619866354","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665619866354","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:20:10Z","timestamp":1777393210000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1055665619866354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,30]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1177\/1055665619866354"],"URL":"https:\/\/doi.org\/10.1177\/1055665619866354","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,30]]}}}