{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:38:15Z","timestamp":1790750295785,"version":"4.1.0"},"reference-count":17,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,8,18]],"date-time":"2019-08-18T00:00:00Z","timestamp":1566086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the utility and efficacy of bioabsorbable hydroxyapatite and collagen complex (HA\/Col) for secondary bone grafting in unilateral alveolar clefts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>Between 2015 and 2016, 21 patients with unilateral cleft lips and alveolar clefts were enrolled. In group I, a cancellous iliac bone graft was placed at the alveolar cleft (6 males, 5 females). In group II, a bioabsorbable HA\/Col was placed at the alveolar cleft (4 males, 7 females).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The groups did not differ in age, cleft volume, or surgical duration. There was a significant difference in intraoperative blood loss between the 2 groups (6.7 \u00b1 1.89 mL in group II vs 38.8 \u00b1 9.73 mL in group I [ P &lt; .01]). The use of patient-controlled intravenous analgesia was also significantly lower in group II than in group I (2.2 \u00b1 1.9 times vs 12.2 \u00b1 4.4 times [ P &lt; .01]). Only 1 female in group II who had maxillary sinusitis did not achieve osteosynthesis. With the exception of this patient, the 12-month bone volumes in groups I and II were 0.567 \u00b1 0.066 and 0.596 \u00b1 0.073 mL, respectively, without significant difference ( P = .18).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Compared with an autogenous bone, bioabsorbable HA\/Col significantly reduces postoperative pain. In addition, the use of HA\/Col alone produced the same result as an autologous bone and is effective in filling the alveolar cleft.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665619866372","type":"journal-article","created":{"date-parts":[[2019,8,18]],"date-time":"2019-08-18T23:55:55Z","timestamp":1566172555000},"page":"114-117","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Assessment of Bioabsorbable Hydroxyapatite for Secondary Bone Grafting in Unilateral Alveolar Clefts"],"prefix":"10.1177","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9516-9260","authenticated-orcid":false,"given":"Yoshiaki","family":"Sakamoto","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Shinjuku, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruo","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Tokyo Dental College, Mihama Ward, Chiba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tekenobu","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Tokyo Dental College, Mihama Ward, Chiba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuo","family":"Kishi","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Shinjuku, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,8,18]]},"reference":[{"key":"bibr1-1055665619866372","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tec.2009.0824"},{"key":"bibr2-1055665619866372","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-200311000-00005"},{"issue":"3","key":"bibr3-1055665619866372","first-page":"175","volume":"23","author":"Bergland O","year":"1986","journal-title":"Cleft Palate J"},{"issue":"2","key":"bibr4-1055665619866372","first-page":"87","volume":"30","author":"Boyne PJ","year":"1972","journal-title":"J Oral Surg"},{"key":"bibr5-1055665619866372","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2003.tb00198.x"},{"key":"bibr6-1055665619866372","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9785(85)80003-X"},{"key":"bibr7-1055665619866372","doi-asserted-by":"publisher","DOI":"10.1597\/06-047.1"},{"key":"bibr8-1055665619866372","doi-asserted-by":"crossref","unstructured":"Hammoudeh JA, Fahradyan A, Gould DJ, Liang F, Imahiyerobo T, Urbinelli L, Nguyen JT, Magee WIII, Yen S, Urata MM. A comparative analysis of recombinant human bone morphogenetic protein-2 with a demineralized bone matrix versus iliac crest bone graft for secondary alveolar bone grafts in patients with cleft lip and palate: review of 501 cases. 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