{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:26:52Z","timestamp":1777523212938,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,8,11]],"date-time":"2019-08-11T00:00:00Z","timestamp":1565481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:p>\n                    Cant\u00fa syndrome (CS) is a rare autosomal dominant disorder caused by a heterozygous pathogenic variant in the\n                    <jats:italic>ABCC9<\/jats:italic>\n                    or\n                    <jats:italic>KCNJ8<\/jats:italic>\n                    gene. The disorder is characterized by congenital generalized hypertrichosis, coarse acromegaloid facial features (broad nasal bridge, epicanthal folds, wide mouth, macroglossia), skeletal abnormalities (calvarial thickening, metaphyseal flares, coxa valga, scoliosis), tortuous vasculature (meningeal arteriovenous malformations), and cardiac abnormalities (patent ductus arteriosus, pericardial effusion). Despite the constellation of craniofacial features, there are currently no documented cases of a patient with CS having orthognathic surgery. The purpose of this report is to highlight the multidisciplinary collaboration, including establishment of a genetic diagnosis, cardiac management, and orthodontic therapy, in performing successful orthognathic surgery in a patient with CS.\n                  <\/jats:p>","DOI":"10.1177\/1055665619868043","type":"journal-article","created":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T00:16:41Z","timestamp":1565569001000},"page":"249-254","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["You \u201cCantu\u201d: Multidisciplinary Collaboration Resulting in Successful Orthognathic Surgery"],"prefix":"10.1177","volume":"57","author":[{"given":"Christopher","family":"Kurian","sequence":"first","affiliation":[{"name":"University of Missouri, Kansas City School of Medicine, Kansas City, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gina","family":"Pinamonti","sequence":"additional","affiliation":[{"name":"Private Practice, Pittsburgh, KS, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Starling Hughes","sequence":"additional","affiliation":[{"name":"Division of Genetics, Children\u2019s Mercy Hospital, Kansas City, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Martin","sequence":"additional","affiliation":[{"name":"Heart Center, Children\u2019s Mercy Hospital, Kansas City, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2953-8456","authenticated-orcid":false,"given":"Michael","family":"Lypka","sequence":"additional","affiliation":[{"name":"University of Missouri, Kansas City School of Medicine, Kansas City, MO, USA"},{"name":"Division of Orthodontics, University of Missouri-Kansas City School of Dentistry, Kansas City, MO, USA"},{"name":"Division of Pediatric Plastic and Craniofacial Surgery, Children\u2019s Mercy Hospital, Kansas City, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,8,11]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-016-3624-3"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCD.0b013e32833d015c"},{"key":"e_1_3_2_4_1","volume-title":"GeneReviews","author":"Grange DK","year":"2014","unstructured":"Grange DK, Nichols CG, Singh GK. Cant\u00fa syndrome and related disorders. In: GeneReviews. Seattle, WA; 2014."},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31348"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2324"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.36228"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002861"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1254\/fpj.122.243"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.112.300514"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665619868043","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1055665619868043","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665619868043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:20:11Z","timestamp":1777393211000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1055665619868043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,11]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1177\/1055665619868043"],"URL":"https:\/\/doi.org\/10.1177\/1055665619868043","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,11]]}}}