{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T02:40:25Z","timestamp":1778899225165,"version":"3.51.4"},"reference-count":40,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:00:00Z","timestamp":1568073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100008364","name":"Tandl\u00e6geforeningen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100008364","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To examine the association of cleft severity at infancy and velopharyngeal competence in preschool children with unilateral cleft lip and palate operated with early or delayed hard palate repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Subgroup analysis within a multicenter randomized controlled trial of primary surgery (Scandcleft).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Tertiary health care. One surgical center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>One hundred twenty-five infants received cheilo-rhinoplasty and soft palate repair at age 3 to 4 months and were randomized to hard palate closure at age 12 or 36 months. Cleft size and cleft morphology were measured 3 dimensionally on digital models, obtained by laser surface scanning of preoperative plaster models (mean age: 1.8 months).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measurements:<\/jats:title>\n                    <jats:p>Velopharyngeal competence (VPC) and hypernasality assessed from a naming test (VPC-Sum) and connected speech (VPC-Rate). In both scales, higher scores indicated a more severe velopharyngeal insufficiency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      No difference between surgical groups was shown. A low positive correlation was found between posterior cleft width and VPC-Rate (Spearman = .23;\n                      <jats:italic>P<\/jats:italic>\n                      = .025). The role of the covariate \u201ccleft size at tuberosity level\u201d was confirmed in an ordinal logistic regression model (odds ratio [OR] = 1.17; 95% confidence interval [CI]:1.01-1.35). A low negative correlation was shown between anteroposterior palatal length and VPC-Sum (Spearman = \u2212.27;\n                      <jats:italic>P<\/jats:italic>\n                      = .004) and confirmed by the pooled scores VPC-Pooled (OR = 0.82; 95% CI: 0.69-0.98) and VPC-Dichotomic (OR = 0.82; 95% CI: 0.68-0.99).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Posterior cleft dimensions can be a modest indicator for the prognosis of velopharyngeal function at age 5 years, when the soft palate is closed first, independently on the timing of hard palate repair. Antero-posterior palatal length seems to protect from velopharyngeal insufficiency and hypernasality. However, the association found was significant but low.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665619874143","type":"journal-article","created":{"date-parts":[[2019,9,11]],"date-time":"2019-09-11T00:15:21Z","timestamp":1568160921000},"page":"420-429","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Influence of Infant Cleft Dimensions on Velopharyngeal Function in 5-Year-Old Danish Children Born With Unilateral Cleft Lip and Palate"],"prefix":"10.1177","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5514-2960","authenticated-orcid":false,"given":"Susanna","family":"Botticelli","sequence":"first","affiliation":[{"name":"Section of Orthodontics, Aarhus University, Denmark"},{"name":"Cleft Lip and Palate Center, IKH, Region Midt, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annelise","family":"K\u00fcseler","sequence":"additional","affiliation":[{"name":"Section of Orthodontics, Aarhus University, Denmark"},{"name":"Cleft Lip and Palate Center, IKH, Region Midt, Aarhus, Denmark"},{"name":"Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirsten","family":"M\u00f8lsted","sequence":"additional","affiliation":[{"name":"Copenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helene Soegaard","family":"Andersen","sequence":"additional","affiliation":[{"name":"Copenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Boers","sequence":"additional","affiliation":[{"name":"Copenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antje","family":"Shoeps","sequence":"additional","affiliation":[{"name":"Copenhagen Cleft Palate Center, University Hospital of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berit Kildegaard","family":"Emborg","sequence":"additional","affiliation":[{"name":"Cleft Lip and Palate Center, IKH, Region Midt, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mia","family":"Kisling-M\u00f8ller","sequence":"additional","affiliation":[{"name":"Cleft Lip and Palate Center, IKH, Region Midt, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas Klit","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Section of Orthodontics, Aarhus University, Denmark"},{"name":"Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikael","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery and Burns Treatment, University Hospital of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9013-8764","authenticated-orcid":false,"given":"Elisabeth","family":"Willadsen","sequence":"additional","affiliation":[{"name":"Department of Nordic Studies and Linguistics, University of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,9,10]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1055665618770795"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1597\/13-121"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1597\/06-244"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199106000-00005"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2001_038_0358_napdtv_2.0.co_2"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2002_039_0409_peosav_2.0.co_2"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/136828298247776"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1597\/06-086.1"},{"issue":"2","key":"e_1_3_4_10_1","first-page":"126","article-title":"Strategies in cleft palate speech\u2014with special reference to Danish","volume":"24","author":"Hutters B","year":"1987","unstructured":"Hutters B, Brondsted K. Strategies in cleft palate speech\u2014with special reference to Danish. Cleft Palate J. 1987;24(2):126\u2013136.","journal-title":"Cleft Palate J"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/22.1.93"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.2012.169"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1597\/09-069"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2011.01468.x"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2010.01.024"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000001355"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/02844310600973621"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1597\/11-085"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/02699206.2017.1302510"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2016.1254645"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1997_034_0122_rcithp_2.3.co_2"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1998_035_0095_vfincp_2.3.co_2"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e318199669b"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200111000-00011"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.07.016"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2008.05.048"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1597\/06-205.1"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2016.1254646"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2017.03.006"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1597\/08-219_1"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1597\/13-325"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1080\/13682820400016522"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12112"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1597\/14-120"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2016.1263202"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2016.1254644"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2018.09.027"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2016.1254647"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000003646"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0000000000000407"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1044\/jslhr.4304.989"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665619874143","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1055665619874143","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665619874143","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:20:17Z","timestamp":1777393217000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1055665619874143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,10]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1177\/1055665619874143"],"URL":"https:\/\/doi.org\/10.1177\/1055665619874143","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,10]]}}}