{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:48:10Z","timestamp":1790718490060,"version":"4.1.0"},"reference-count":56,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T00:00:00Z","timestamp":1574208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100006636","name":"Forskningsr\u00e5det om H\u00e4lsa, Arbetsliv och V\u00e4lf\u00e4rd","doi-asserted-by":"crossref","award":["2011\u20131443"],"award-info":[{"award-number":["2011\u20131443"]}],"id":[{"id":"10.13039\/501100006636","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To investigate in-depth speech results in the Scandcleft Trial 2 with comparisons between surgical protocols and centers and with benchmarks from peers without cleft palate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>A prospective randomized clinical trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Two Swedish and one Finnish Cleft Palate center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>One hundred twelve participants were 5-years-old born with unilateral cleft lip and palate randomized to either lip repair and soft palate closure at 4 months and hard palate closure at 12 months or lip repair at 3 to 4 months (Arm A), or a closure of both the soft and hard palate at 12 months (Arm C).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures:<\/jats:title>\n                    <jats:p>A composite measure dichotomized into velopharyngeal competency (VPC) or velopharyngeal incompetency (VPI), overall assessment of velopharyngeal function (VPC-Rate), percentage of consonants correct (PCC score), and consonant errors. In addition, number of speech therapy visits, average hearing thresholds, and secondary surgeries were documented to assess burden of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Across the trial, 53.5% demonstrated VPC and 46.5% VPI with no significant differences between arms or centers. In total, 27% reached age-appropriate PCC scores with no statistically significant difference between the arms. The Finnish center had significantly higher PCC scores, the Swedish centers had higher percentages of oral consonant errors. Number of speech therapy visits was significantly higher in the Finnish center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>At age 5, poor speech outcomes with some differences between participating centers were seen but could not be attributed to surgical protocol. As one center had very few participants, the results from that center should be interpreted with caution.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665619888316","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T08:36:54Z","timestamp":1574239014000},"page":"458-469","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Scandcleft Project Trial 2\u2014Comparison of Speech Outcome in 1- and 2-Stage Palatal Closure in 5-Year-Olds With UCLP"],"prefix":"10.1177","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3140-0643","authenticated-orcid":false,"given":"Inger Lundeborg","family":"Hammarstr\u00f6m","sequence":"first","affiliation":[{"name":"Division of Speech and Language Pathology, Link\u00f6ping University, Link\u00f6ping, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill","family":"Nyberg","sequence":"additional","affiliation":[{"name":"Stockholm Craniofacial Team, Karolinska University Hospital, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suvi","family":"Alaluusua","sequence":"additional","affiliation":[{"name":"Cleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorma","family":"Rautio","sequence":"additional","affiliation":[{"name":"Cleft Palate and Craniofacial Center, Helsinki University Central Hospital, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Neovius","sequence":"additional","affiliation":[{"name":"Stockholm Craniofacial Team, Karolinska University Hospital, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Berggren","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, University Hospital, Link\u00f6ping, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7860-1573","authenticated-orcid":false,"given":"Christina","family":"Persson","sequence":"additional","affiliation":[{"name":"Speech and Language Pathology Unit, Institute of Neuroscience and Physiology, University of Gothenburg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9013-8764","authenticated-orcid":false,"given":"Elisabeth","family":"Willadsen","sequence":"additional","affiliation":[{"name":"Department of Nordic Studies and Linguistics, University of Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anette","family":"Lohmander","sequence":"additional","affiliation":[{"name":"Division of Speech and Language Pathology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,11,20]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1597\/13-121"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1597\/05-164"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118785065.ch2"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-4356(96)90242-9"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/0269920031000111348"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2002_039_0409_peosav_2.0.co_2"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/001316447303300309"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/136828298247776"},{"key":"e_1_3_2_10_1","first-page":"68","volume-title":"Management of Cleft Lip and Palate","author":"Grunwell P","year":"2001","unstructured":"Grunwell P, Sell DA. Speech and cleft palate\/velopharyngeal anomalies. In: Watson ACH, Sell DA, Grunwell P, eds. Management of Cleft Lip and Palate. London, England: Whurr Publishers; 2001:68\u201386."},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1998_035_0040_ioclap_2.3.co_2"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118785065.part1"},{"issue":"2","key":"e_1_3_2_13_1","first-page":"126","article-title":"Strategies in cleft palate speech\u2014with special reference to Danish","volume":"24","author":"Hutters B","year":"1987","unstructured":"Hutters B, Br\u00f8ndsted K. Strategies in cleft palate speech\u2014with special reference to Danish. Cleft Palate J. 1987;24(2):126\u2013136.","journal-title":"Cleft Palate J"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1597\/02-164.1"},{"key":"e_1_3_2_15_1","unstructured":"IPA. extIPA Symbols for Disordered Speech [Internet]. International Phonetic Association; 2008. https:\/\/www.internationalphoneticassociation.org\/sites\/default\/files\/extIPAChart2008.pdf. Accessed February 12 2019."},{"key":"e_1_3_2_16_1","unstructured":"IPA. The International Phonetic Alphabet [Internet]. International Phonetic Association; 2015. https:\/\/www.internationalphoneticassociation.org\/sites\/default\/files\/IPA_Doulos_2015.pdf. Accessed February 12 2019."},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1597\/04-141.1"},{"issue":"4","key":"e_1_3_2_18_1","first-page":"278","article-title":"Longitudinal speech performance in patients with cleft palate: comparisons based on secondary management","volume":"23","author":"Karnell M","year":"1986","unstructured":"Karnell M, Van Demark D. Longitudinal speech performance in patients with cleft palate: comparisons based on secondary management. Cleft Palate J. 1986;23(4):278\u2013288.","journal-title":"Cleft Palate J"},{"key":"e_1_3_2_19_1","first-page":"736","volume-title":"Multidisciplinary Management of Cleft Lip and Palate","author":"Kemp-Fincham SI","year":"1990","unstructured":"Kemp-Fincham SI, Kuehn DP, Trost-Cardamone JE. Speech development and the timing of primary palatoplasty. In: Bardach J, Morris HL, eds. Multidisciplinary Management of Cleft Lip and Palate. Philadelphia, PA: WB Saunders; 1990:736\u2013745."},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2016.1194280"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/13682822.2010.507615"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/17549507.2015.1081287"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/1460-6984.12068"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.12968\/ijtr.2012.19.9.488"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2013.840737"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/02699206.2017.1302510"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/02699206.2016.1205666"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2016.1254645"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1597\/06-123.1"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1597\/08-039.1"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118785065.ch4"},{"key":"e_1_3_2_32_1","first-page":"193","volume-title":"Talkommunikation [Speech communication]","author":"McAllister R","year":"1998","unstructured":"McAllister R. Talkommunikation [Speech communication]. Lund, Sweden: Studentlitteratur; 1998: 193\u2013200."},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198107000-00001"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2003_040_0460_ppalso_2.0.co_2"},{"key":"e_1_3_2_35_1","first-page":"57","volume-title":"Spr\u00e5kutveckling och Spr\u00e5kst\u00f6rning hos Barn [Language development and language impairment in children]","author":"Nettelbladt U","year":"2007","unstructured":"Nettelbladt U. Phonological development. In: Nettelbladt U, Salameh EK, eds. Spr\u00e5kutveckling och Spr\u00e5kst\u00f6rning hos Barn [Language development and language impairment in children]. Lund, Sweden: Studentlitteratur; 2007:57\u201394."},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.07.016"},{"key":"e_1_3_2_37_1","author":"Peterson-Falzone SJ","year":"2010","unstructured":"Peterson-Falzone SJ, Karnell MP, Hardin-Jones M. Cleft Palate Speech. 4th edn. St Louis, Missouri: Elsevier; 2010.","journal-title":"Cleft Palate Speech"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2016.1254646"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2017.03.006"},{"key":"e_1_3_2_40_1","volume-title":"The Bus Story: A Test of Continuous Speech","author":"Renfrew C","year":"1969","unstructured":"Renfrew C. The Bus Story: A Test of Continuous Speech. North Place, Old Headington: Oxford; 1969."},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200008000-00026"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/0142723710396793"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2008.02.010"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12112"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12186"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2016.1263202"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1044\/jslhr.4004.708"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1080\/0269920031000138132"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1044\/jshd.4703.242"},{"key":"e_1_3_2_50_1","first-page":"413","volume-title":"Comprehensive Cleft Care","author":"Sommerlad BC","year":"2008","unstructured":"Sommerlad BC. Cleft palate repair with minimal hard palate dissection and radical muscle reconstruction. In: Losee JE, Kirschner RE, eds. Comprehensive Cleft Care. Columbus, OH: McGraw-Hill; 2008:413\u2013429."},{"key":"e_1_3_2_51_1","volume-title":"Finnish Sound Structure\u2014Phonetics, Phonology, Phonotactics and Prosody. Studia Humaniora Ouluensia 9","author":"Suomi K","year":"2008","unstructured":"Suomi K, Toivanen J, Ylitalo R. Finnish Sound Structure\u2014Phonetics, Phonology, Phonotactics and Prosody. Studia Humaniora Ouluensia 9. Oulu, Finland: University of Oulu; 2008."},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118785065.ch11"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcomdis.2007.02.002"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2016.1254647"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1597\/09-120"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)03748-4"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1177\/1055665618767116"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665619888316","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1055665619888316","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665619888316","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:20:19Z","timestamp":1777393219000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1055665619888316"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,20]]},"references-count":56,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1177\/1055665619888316"],"URL":"https:\/\/doi.org\/10.1177\/1055665619888316","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,20]]}}}