{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:27:35Z","timestamp":1777523255459,"version":"3.51.4"},"reference-count":51,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T00:00:00Z","timestamp":1596499200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the microbiota profile of residual alveolar slits and teeth adjacent to the cleft in fissured individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Designs:<\/jats:title>\n                    <jats:p>This study used a cross-sectional design.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>Twenty individuals, aged 14 to 24 years, who had a residual fissure in the maxillary alveolar ridge region were selected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures:<\/jats:title>\n                    <jats:p>Three sites per individual were selected for microbiological collection (the site of the residual cleft and the 2 nearest teeth). The samples were analyzed using the Checkerboard DNA\u2013DNA hybridization technique for 73 species of bacteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      All the species analyzed were found in the 2 niches (slits and teeth). The bacterial species present in the largest number in the residual cracks were\n                      <jats:italic>Prevotella melaninogenica<\/jats:italic>\n                      ,\n                      <jats:italic>Prevotella nigrescens<\/jats:italic>\n                      , and\n                      <jats:italic>Streptococcus mitis<\/jats:italic>\n                      . With regard to the bacterial profiles in the mesial and distal faces, the most prevalent species were\n                      <jats:italic>P nigrescens<\/jats:italic>\n                      ,\n                      <jats:italic>Veillonella parvula<\/jats:italic>\n                      , and\n                      <jats:italic>Fusobacterium nucleatum sp vicentii<\/jats:italic>\n                      . The analysis of all the collected samples demonstrated very similar profiles for the mesial and distal faces, with these 2 sites even presenting the same species in greater frequencies. Higher counts of 20 bacterial species (Wilcoxon test) were observed in the dental niche, in relation to the fissure, particularly,\n                      <jats:italic>P nigrescens<\/jats:italic>\n                      ,\n                      <jats:italic>V parvula<\/jats:italic>\n                      ,\n                      <jats:italic>F nucleatum sp vicentii<\/jats:italic>\n                      , and\n                      <jats:italic>Neisseria mucosa<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Some species were significantly more prevalent in the residual alveolar fissures and in adjacent teeth. The comparison between the profiles of the 2 niches demonstrated large differences in the most frequent species in the teeth, and no qualitative differences with regard to specific pathogens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665620945568","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T07:49:56Z","timestamp":1596527396000},"page":"1182-1189","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of the Microbiological Profile of Alveolar Residual Screws and Cleft-Adjacent Teeth in Individuals With Complete Unilateral Fissures"],"prefix":"10.1177","volume":"57","author":[{"given":"Ronaldo","family":"Iurovschi","sequence":"first","affiliation":[{"name":"Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia Regina","family":"Joaquim","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo","family":"de Faveri","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2988-9205","authenticated-orcid":false,"given":"Tamires Szeremeske","family":"de Miranda","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magda","family":"Feres","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciene Cristina","family":"de Figueiredo","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,8,4]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamafacial.2014.1436"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1597\/07-226.1"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/039139881003300903"},{"issue":"3","key":"e_1_3_3_5_1","first-page":"145","article-title":"Current concepts on cleft lip and palate etiology","volume":"33","author":"Candotto V","year":"2019","unstructured":"Candotto V, Oberti L, Gabrione F, Greco G, Rossi D, Romano M, Mummolo S. 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