{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:32:07Z","timestamp":1777523527160,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T00:00:00Z","timestamp":1606953600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To analyze the incidence of submucous cleft palate (SMCP) in a large national database and raise awareness among referring providers: pediatricians, speech pathologists, and dentists to minimize delay in diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Tertiary setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients:<\/jats:title>\n                    <jats:p>Patients were extracted from the \u201cDutch Association for Cleft and Craniofacial Anomalies\u201d database. A total of 6916 patients were included from 1997 until 2018 and divided into 2 groups (ie, SMCP versus cleft palate [CP]). Patients born before 1997 and adopted patients were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions:<\/jats:title>\n                    <jats:p>Clefts were classified as either hard of soft palatal involvement based on anatomical landmarks at first consultation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures:<\/jats:title>\n                    <jats:p>Primary outcomes were the patient characteristics in both groups (ie, gender, birth weight, gestational age, and additional anomalies). Secondary outcome was the time of diagnosis among subgroups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In total, 532 patients were diagnosed with SMCP (7.7%). Birth weight, gestational age, and additional anomalies did not differ between subgroups, but there were more males in the SMCP group ( P &lt; .001). The median age of diagnosis of the SMCP group was significantly higher than of the CP group (987 vs 27 days; P &lt; .001). Over the course of 22 years, the time of diagnosis for SMCP did not decrease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Submucous cleft palate represents &lt;10% of the Dutch cleft population and 19.4% of all CP. Time of diagnosis for SMCP is significantly longer when compared with time of diagnosis of CP, and this has not changed over the study period of 22 years.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665620977760","type":"journal-article","created":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T04:12:02Z","timestamp":1606968722000},"page":"1121-1127","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Incidence of Symptomatic Submucous Cleft Palate in the Netherlands: A Retrospective Cohort Study Over a Period of 22 Years"],"prefix":"10.1177","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1199-2335","authenticated-orcid":false,"given":"Johannes A.","family":"Smit","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, Amsterdam University Medical Center, Emma Children\u2019s Hospital, Amsterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Puck P.","family":"Mulder","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Amsterdam University Medical Center, Emma Children\u2019s Hospital, Amsterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feike","family":"de Graaf","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Amsterdam University Medical Center, Emma Children\u2019s Hospital, Amsterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernadette S.","family":"de Bakker","sequence":"additional","affiliation":[{"name":"Department of Medical Biology, Section Clinical Anatomy & Embryology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corstiaan C.","family":"Breugem","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Amsterdam University Medical Center, Emma Children\u2019s Hospital, Amsterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,12,3]]},"reference":[{"key":"bibr1-1055665620977760","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0503(85)80011-4"},{"key":"bibr2-1055665620977760","volume-title":"Bluestone and Stool\u2019s: Pediatric Otolaryngology","author":"Bluestone CD","year":"2014","edition":"5"},{"key":"bibr3-1055665620977760","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1226(53)80060-3"},{"key":"bibr4-1055665620977760","unstructured":"Centraal Bureau voor Statistiek: Bevalling en geboorte 1983\u20132013. 2013. 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