{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:32:04Z","timestamp":1777523524128,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2020,12,21]],"date-time":"2020-12-21T00:00:00Z","timestamp":1608508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the occurrence of cervical vertebrae anomalies (CVA) in patients with unilateral (UCLP) and bilateral cleft lip and palate (BCLP) using cone beam computed tomography (CBCT) examinations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>\n                      Retrospective assessment of CBCT images. Descriptive statistics were calculated. Fisher exact test or \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      test was performed to evaluate the differences among each CVA between sex and type of cleft.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>School of Dentistry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>One hundred fifty-one patients with cleft lip and palate (103 UCLP\/48 BCLP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions:<\/jats:title>\n                    <jats:p>No relevant intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures:<\/jats:title>\n                    <jats:p>Cone beam computed tomography images were assessed for the presence or absence of 12 most commonly observed CVA: spina bifida, dehiscence, cleft of the posterior arch, cleft of the anterior arch, fusion between cervical vertebrae, block fusion, occipitalization, narrowing of the intervertebral space, posterior ponticle, os odontoideum, ossiculum terminale, and subdental cartilaginous remnants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The presence of subdental cartilaginous remnants was the most frequently observed alteration\u2014found in 81.45% of the sample\u2014and it was the only CVA with statistically significant frequencies in the individuals with BCLP. Considering only the other CVA, 22.51% presented 1 and 5.29% presented 2 or more CVA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Patients with cleft lip and palate may present an overall high incidence of CVAs. However, when comparing the distribution of the CVAs among sex and types of cleft, the only significant difference noted was a higher incidence of subdental cartilaginous remnants among patients with BCLP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1055665620980226","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T02:36:55Z","timestamp":1608604615000},"page":"1102-1109","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Three-Dimensional Assessment of Cervical Vertebrae Anomalies in Patients With Cleft Lip and Palate"],"prefix":"10.1177","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5305-7671","authenticated-orcid":false,"given":"Gabriella L.","family":"de Rezende Barbosa","sequence":"first","affiliation":[{"name":"Department of Oral Diagnosis, School of Dentistry, Federal University of Uberlandia. Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz A.","family":"Pimenta","sequence":"additional","affiliation":[{"name":"Division of Comprehensive Oral Health, School of Dentistry, University of North Carolina. Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald A.","family":"Tyndall","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Sciences, School of Dentistry, University of North Carolina. Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trishul V.","family":"Allareddy","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology, Radiology and Medicine, College of Dentistry, The University of Iowa, Iowa City, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2299-5769","authenticated-orcid":false,"given":"Saulo L.","family":"Sousa Melo","sequence":"additional","affiliation":[{"name":"Department of Integrative Biomedical and Diagnostic Sciences, School of Dentistry, Oregon Health and Science University. Portland, OR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,12,21]]},"reference":[{"key":"bibr1-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2018.07.038"},{"key":"bibr2-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20190085"},{"key":"bibr3-1055665620980226","first-page":"566","volume-title":"Clinical Anatomy of the Spine, Spinal Cord, and ANS","author":"Cramer GD","year":"2013"},{"key":"bibr4-1055665620980226","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10005-1258"},{"key":"bibr5-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1016\/0736-4679(89)90258-8"},{"key":"bibr6-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1590\/S1678-77572012000100003"},{"key":"bibr7-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-005-0990-7"},{"key":"bibr8-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.21.1.1397450"},{"key":"bibr9-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(10)80229-0"},{"key":"bibr10-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1597\/08-018.1"},{"key":"bibr11-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1148\/rg.233025121"},{"key":"bibr12-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1044\/jshr.1401.14"},{"key":"bibr13-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2012.09.017"},{"key":"bibr14-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1597\/05-023"},{"key":"bibr15-1055665620980226","first-page":"273","volume":"36","author":"Ross RB","year":"1965","journal-title":"Cleft Palate J"},{"key":"bibr16-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2017.10.037"},{"issue":"3","key":"bibr17-1055665620980226","first-page":"206","volume":"23","author":"Sandham A","year":"1986","journal-title":"Cleft Palate J"},{"key":"bibr18-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1016\/j.cden.2008.05.005"},{"key":"bibr19-1055665620980226","doi-asserted-by":"publisher","DOI":"10.3171\/SPI-07\/10\/399"},{"key":"bibr20-1055665620980226","volume-title":"Morphological Anomalies of Upper Cervical Vertebrae in Children Born With Non-syndromic Cleft Lip and\/or Palate Compared With Children Without Cleft","author":"Sideri M","year":"2013"},{"key":"bibr21-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1993_030_0274_lotcsa_2.3.co_2"},{"key":"bibr22-1055665620980226","doi-asserted-by":"publisher","DOI":"10.4103\/2348-2125.126561"},{"key":"bibr23-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2001_038_0498_tpoaot_2.0.co_2"},{"key":"bibr24-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(96)70069-0"},{"key":"bibr25-1055665620980226","doi-asserted-by":"publisher","DOI":"10.1597\/04-085r2.1"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665620980226","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1055665620980226","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1055665620980226","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:21:13Z","timestamp":1777393273000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1055665620980226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,21]]},"references-count":25,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1177\/1055665620980226"],"URL":"https:\/\/doi.org\/10.1177\/1055665620980226","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,21]]}}}