{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:10:38Z","timestamp":1787019038767,"version":"build-2736575974"},"reference-count":55,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T00:00:00Z","timestamp":1621900800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"State of Amazonas Research Foundation\u00a0\u2013 FAPEAM","award":["23038.00302\/2014-32"],"award-info":[{"award-number":["23038.00302\/2014-32"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To investigate the speech outcomes in individuals with cleft lip and palate (CLP) from the Amazon region and determine their correlation with sociodemographic factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Cross-sectional, prospective, single-blind study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Tertiary care institute in Manaus, Amazonas, Brazil.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients:<\/jats:title>\n                    <jats:p>Four hundred twenty individuals with CLP, aged 4 to 57 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures:<\/jats:title>\n                    <jats:p>The samples were judged by 3 speech pathologists experienced in the speech assessment of individuals with CLP. Hypernasality was scored using a 4-point scale, being 1 = absent, 2 = mild, 3 = moderate, and 4 = severe, and the active speech symptoms were classified as absent or present. The final score for each speech symptom was reached by consensus among the 3 examiners Descriptive analysis of sociodemographic data included origin, socioeconomic status, type of cleft, surgical technique employed, the age they underwent primary and secondary palatoplasty, and palatal fistula.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Absence of hypernasality was observed in 41% of the individuals, 18% had mild, 28% moderate, and 13% severe hypernasality. Active speech symptoms were observed in 57% of the individuals. Significant correlations were found between speech outcomes and the variables such as origin, socioeconomic status, age at primary and secondary palatoplasty, and presence of fistula.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Most individuals with repaired CLP from the Amazon region presented speech disorders, characterized by hypernasality and active errors. Patients living outside the state capital, of low socioeconomic level, underwent palatoplasty late and with presence of palatal fistula tended to have the worst speech outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656211017791","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T05:08:59Z","timestamp":1621919339000},"page":"595-602","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Treatment of Cleft Lip and Palate in the Amazon Region in Brazil: Speech Results and Sociodemographic Aspects"],"prefix":"10.1177","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9863-7100","authenticated-orcid":false,"given":"Laryssa Lopes","family":"de Ara\u00fajo","sequence":"first","affiliation":[{"name":"Ya\u00e7uri da Amaz\u00f4nia Institute, Manaus, Brazil"},{"name":"Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivaldo","family":"Alonso","sequence":"additional","affiliation":[{"name":"Department of Plastic\u00a0Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5927-3877","authenticated-orcid":false,"given":"Ana Paula","family":"Fukushiro","sequence":"additional","affiliation":[{"name":"Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"},{"name":"Speech-Language Pathology Department, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,5,25]]},"reference":[{"key":"bibr1-10556656211017791","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2012.09.038"},{"key":"bibr2-10556656211017791","doi-asserted-by":"publisher","DOI":"10.4103\/0189-6725.125447"},{"key":"bibr3-10556656211017791","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.07.025"},{"key":"bibr4-10556656211017791","doi-asserted-by":"publisher","DOI":"10.1597\/15-292"},{"key":"bibr5-10556656211017791","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181845a21"},{"key":"bibr6-10556656211017791","first-page":"73","volume-title":"Fissuras Labiopalatinas: Uma Abordagem Interdisciplinar","author":"Bertier CE","year":"2007"},{"issue":"1","key":"bibr7-10556656211017791","first-page":"43","volume":"31","author":"Bosi VZ","year":"2016","journal-title":"Rev Bras Cir Pl\u00e1st"},{"key":"bibr8-10556656211017791","unstructured":"Brosco TVS. 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Influ\u00eancia do tipo de fissura l\u00e1bio palatina sobre os resultados de fala ap\u00f3s a palatoplastia prim\u00e1ria. Hospital de Reabilita\u00e7\u00e3o de Anomalias Craniofaciais, Universidade de S\u00e3o Paulo; 2018. 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