{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T22:39:47Z","timestamp":1782513587026,"version":"3.54.5"},"reference-count":28,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T00:00:00Z","timestamp":1631491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Craniofacial clefts are rare congenital anomalies that might involve both soft tissue and skeletal components. The association of Tessier cleft number 3 and 4 with choanal atresia appears to be unusual and only few clinical cases have been reported in published literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Report a series of 13 cases of choanal atresia in patients with Tessier numbers 3 or 4 clefts and the literature review on this topic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A literature review was undertaken via PUBMED database before April 2020 addressing the association between Tessier numbers 3 or 4 clefts and choanal atresia. Retrospective chart review of patients diagnosed with both comorbidities at a tertiary hospital expertised in craniofacial anomalies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Literature review yielded 10 studies describing the relationship between choanal atresia and Tessier 3 and 4 facial clefts. We identified 98 patients diagnosed with medial oro-ocular facial clefts (Tessier 3 and 4) and 119 with choanal atresia at our institution over a 20 years time period. Altogether, 13 individuals were diagnosed with both malformations, 3 patients with number 3 cleft, and 10 patients with number 4 cleft. It represents 13.26% of the cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study highlights the features of Tessier 3 and 4 facial clefts associated with choanal atresia. Although the publications regarding this association are very scarce, the authors present the largest series of cases of Tessier number 3 and 4 clefts with choanal atresia showing that association between these conditions could be not so unusual.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656211042172","type":"journal-article","created":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T08:19:16Z","timestamp":1631521156000},"page":"1228-1232","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Tessier 3 and 4 Clefts and Choanal Atresia: An Unusual Association?"],"prefix":"10.1177","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0881-416X","authenticated-orcid":false,"given":"Cristiano","family":"Tonello","sequence":"first","affiliation":[{"name":"University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo Augusto Nery dos Passos","family":"Martins","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Ant\u00f4nio Ferraz de Barros","family":"Baptista","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Mondelli","sequence":"additional","affiliation":[{"name":"Nove de Julho University (UNINOVE), Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy Mizue","family":"Kokitsu Nakata","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3379-3399","authenticated-orcid":false,"given":"Leonardo Bezerra","family":"Feitosa","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivaldo","family":"Alonso","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,9,13]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2014.04.020"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318188209c"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2004.03.004"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1597\/02-105"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1226(70)80074-1"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0007-1226(90)90088-H"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199601000-00019"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2009.53"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199803000-00010"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3181cfa6b1"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197309000-00006"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000164494.45986.91"},{"key":"e_1_3_2_14_1","first-page":"275","article-title":"Rare clefts of the face","volume":"129","author":"Fogh-Anderson P","year":"1965","unstructured":"Fogh-Anderson P. 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