{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T07:05:11Z","timestamp":1793862311887,"version":"4.6.1"},"reference-count":27,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2021,10,18]],"date-time":"2021-10-18T00:00:00Z","timestamp":1634515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"JSPS KAKENHI","award":["19K10356"],"award-info":[{"award-number":["19K10356"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate long-term morphological changes in the soft palate length and nasopharynx in patients with cleft palate. We hypothesized that there would be differences in the morphological development of the soft palate and nasopharynx between patients with and without cleft palate and that these developmental changes would negatively affect the soft palate length to pharyngeal depth ratio involved in velopharyngeal closure for patients with cleft palate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective, case-control study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Institutional practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>Ninety-two patients (Group F) with unilateral cleft lip, alveolus, and palate and 67 patients (Group CLA) with unilateral cleft lip and alveolus not requiring palatoplasty were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>The soft palate length, nasopharyngeal size, and soft palate length to pharyngeal depth ratio were measured via lateral cephalograms obtained at three different periods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Group F showed a shorter soft palate length and smaller nasopharyngeal size than Group CLA at all periods. Both these parameters increased with age, but the increase in amount was significantly less in Group F compared with that in Group CLA. The soft palate length to pharyngeal depth ratio in Group F decreased with age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with cleft palate, the soft palate length to pharyngeal depth ratio, which is involved in velopharyngeal closure, can change with age. Less soft palate length growth and unfavorable relationship between the soft palate and nasopharynx may be masked in early childhood but can manifest later on with age.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656211045287","type":"journal-article","created":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T04:54:56Z","timestamp":1634619296000},"page":"1264-1270","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Long-term Morphological Changes of the Velum and the Nasopharynx in Patients With Cleft Palate"],"prefix":"10.1177","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6437-8614","authenticated-orcid":false,"given":"Takeshi","family":"Harada","sequence":"first","affiliation":[{"name":"Osaka Women\u2019s and Children\u2019s Hospital, Izumi, Osaka, Japan"},{"name":"Kansai Rosai Hospital, Amagasaki, Hyogo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8204-305X","authenticated-orcid":false,"given":"Tadashi","family":"Yamanishi","sequence":"additional","affiliation":[{"name":"Osaka Women\u2019s and Children\u2019s Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Kurimoto","sequence":"additional","affiliation":[{"name":"Osaka Women\u2019s and Children\u2019s Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Setsuko","family":"Uematsu","sequence":"additional","affiliation":[{"name":"Osaka Women\u2019s and Children\u2019s Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuri","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Osaka Women\u2019s and Children\u2019s Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Inoue","sequence":"additional","affiliation":[{"name":"Osaka Women\u2019s and Children\u2019s Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juntaro","family":"Nishio","sequence":"additional","affiliation":[{"name":"Osaka Women\u2019s and Children\u2019s Hospital, Izumi, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,10,18]]},"reference":[{"issue":"2","key":"e_1_3_2_2_1","first-page":"116","article-title":"Craniofacial morphology in twins discordant for cleft lip and\/or palate","volume":"17","author":"Cronin DG","year":"1980","unstructured":"Cronin DG, Hunter WS. 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