{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T02:44:15Z","timestamp":1789699455673,"version":"4.0.1"},"reference-count":37,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T00:00:00Z","timestamp":1637107200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the effect of laser bio-modulation irradiation therapy on the scar after surgical correction of unilateral cleft lip.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>a comparative, open-label study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>we conducted the study in a university based tertiary hospital that recruited early wound healers of unilateral cleft lip correction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>Eighty patients were divided into two groups: In study's group, patients undergo laser bio-modulation irradiation (n\u2009=\u200960); in the control group, patients were followed-up without intervention (n\u2009=\u200920).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>In the study's group, patients underwent low-power diode Laser with wavelength of 806\u2005nm and power of 100\u2005mw.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome<\/jats:title>\n                    <jats:p>The change in the scar of cleft lip patients, which was assessed by clinical examination and ultrasound.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The median pigmentation score was significantly lower in the laser group (median\u2009=\u20091; IQR\u2009=\u20091\u20132) than the control group (median 2; IQR 1\u20133), with p-value of &lt;0.001. Likewise, the median height score was significantly lower in the laser group (median\u2009=\u20091; IQR\u2009=\u20091\u20131) than the control group (median 1.5; IQR 1.5\u20132), with p-value of 0.001. The median pliability score was significantly lower in the laser group (median\u2009=\u20091; IQR\u2009=\u20091\u20131) than the control group (median 2.5; IQR 1\u20133), with p-value of &lt;0.001. Finally, the median vascularity score was significantly lower in the laser group (median\u2009=\u20091; IQR\u2009=\u20091\u20131) than the control group (median 1.5; IQR 1\u20132), with p-value of &lt;0.001.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>laser bio-modulation irradiation therapy demonstrates a potential efficacy in managing the hypertrophic scars after surgical repair of unilateral cleft lip.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656211053536","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T05:53:51Z","timestamp":1637128431000},"page":"21-26","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Evaluating the Effect of Low Power Diode Laser 806\u2005nm on the Healing of Unilateral Cleft Lip Scar: An Open-Label Comparative Study"],"prefix":"10.1177","volume":"60","author":[{"given":"Mariam","family":"Abdul Mohsen","sequence":"first","affiliation":[{"name":"Cairo University Hospitals, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Mohamed","family":"El Husseiny Saafan","sequence":"additional","affiliation":[{"name":"Medical Laser Science of Dental Applications, National Institute of Laser Enhanced Science, Giza, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud S.","family":"El-Basiouny","sequence":"additional","affiliation":[{"name":"General and Plastic Surgery in National Institute of Laser Enhanced Science, Cairo University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamal Hassan","family":"ElTagy","sequence":"additional","affiliation":[{"name":"General Surgery Departement, Pediatric Surgery Unit, Cairo University Specialized Pediatric Hospital, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mennat-Allah Magdy","family":"ElBarbary","sequence":"additional","affiliation":[{"name":"Cairo University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7322-0333","authenticated-orcid":false,"given":"Moutaz","family":"Ragab","sequence":"additional","affiliation":[{"name":"General Surgery Departement, Pediatric Surgery Unit, Cairo University Specialized Pediatric Hospital, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawlat","family":"Emara","sequence":"additional","affiliation":[{"name":"Plastic Surgery Department, Faculty of Medicine, Cairo University, Cairo, 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