{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:34:10Z","timestamp":1777523650273,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T00:00:00Z","timestamp":1638748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study compares patients undergoing early cleft lip repair (ECLR) (&lt;3-months) and traditional lip repair (TLR) (3-6 months) with\/without nasoalveolar molding (NAM) to evaluate the effects of surgical timing on weight gain in hopes of guiding future treatment paradigms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Children's Hospital of Los Angeles, California.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient, Participants<\/jats:title>\n                    <jats:p>A retrospective chart review evaluated patients who underwent ECLR or TLR\u2009\u00b1\u2009NAM from November 2009 through January 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>No intervention was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measure(s)<\/jats:title>\n                    <jats:p>Patient demographics, birth and medical history, perioperative variables, and complications were collected. Infant weights and age-based percentiles were recorded at birth, surgery, 8-weeks, 6-months, 12-months, and 24-months postoperatively. The main outcomes were weight change and weight percentile amongst ECLR and TLR\u2009\u00b1\u2009NAM groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>107 patients met inclusion criteria: ECLR, n\u2009=\u200951 (47.6%); TLR\u2009+\u2009NAM, n\u2009=\u200935 (32.7%); and TLR-NAM, n\u2009=\u200921 (19.6%). ECLR patients had significantly greater changes in weight from surgery to 8-weeks and from surgery to 24-months postoperatively compared with both TLR\u2009\u00b1\u2009NAM ( P\u2009&lt;\u2009.05). Age-matched weights in the ECLR group were significantly greater than TLR\u2009\u00b1\u2009NAM at multiple time points postoperatively ( P\u2009&lt;\u2009.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ECLR significantly increased patient weights 24-months postoperatively when compared to TLR\u2009\u00b1\u2009NAM. Specifically compared to TLR-NAM, ECLR weights were significantly greater at all time points past 6-months postoperatively. The results of this study demonstrate that ECLR can mitigate feeding difficulties and malnutrition traditionally seen in patients with cleft lip.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656211062042","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T05:51:20Z","timestamp":1638769880000},"page":"306-312","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Rethinking the Rule of 10s: Early Cleft Lip Repair Improves Weight Gain"],"prefix":"10.1177","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0739-8763","authenticated-orcid":false,"given":"Katelyn","family":"Kondra","sequence":"first","affiliation":[{"name":"Division of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles, Los Angeles, CA, USA"},{"name":"Division of Plastic and Reconstructive Surgery, Keck School of Medicine, Los Angeles, CA, 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