{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:35:47Z","timestamp":1777523747803,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T00:00:00Z","timestamp":1614902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>Dens invaginatus is a rare developmental anomaly characterized by an infolding of the enamel organ within the crown or root of a tooth, and it is an example of a dental anomaly that has a higher incidence in patients with CL\/P. If undiagnosed, dens invaginatus can lead to severe, acute pain and pulpal necrosis since it can permit direct entry of bacteria into the dental pulp. Treatment of dens invaginatus includes prophylactic sealant or composite restoration, endodontic therapy if pulpal involvement has already occurred, or extraction if aberrant tooth morphology precludes endodontic therapy. Few studies report on the incidence of dens invaginatus in patients with CL\/P. The purpose of this article is to describe 4 cases of dens invaginatus in patients with CL\/P which were encountered in a cleft-craniofacial orthodontic clinic. Each case describes dens invaginatus in a maxillary lateral incisor, and treatments ranged from sealant application to endodontic therapy to extraction. These cases highlight the importance of awareness of this dental anomaly among cleft team providers to facilitate early diagnosis in patients with CL\/P.<\/jats:p>","DOI":"10.1177\/1055665621998534","type":"journal-article","created":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T03:57:36Z","timestamp":1614916656000},"page":"1452-1458","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Dens Invaginatus in Patients With Cleft Lip and Palate: A Case Series"],"prefix":"10.1177","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1572-9745","authenticated-orcid":false,"given":"Ilana M.","family":"Ickow","sequence":"first","affiliation":[{"name":"UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Zinn","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"J. Matthew","family":"Stacy","sequence":"additional","affiliation":[{"name":"UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Martin","sequence":"additional","affiliation":[{"name":"UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph E.","family":"Losee","sequence":"additional","affiliation":[{"name":"UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alene","family":"D\u2019Alesio","sequence":"additional","affiliation":[{"name":"UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Soxman","sequence":"additional","affiliation":[{"name":"Private Practice, Allison Park, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsay A.","family":"Schuster","sequence":"additional","affiliation":[{"name":"UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,3,5]]},"reference":[{"key":"bibr1-1055665621998534","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjp156"},{"key":"bibr2-1055665621998534","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2008.01468.x"},{"issue":"12","key":"bibr3-1055665621998534","first-page":"685","volume":"29","author":"Atkinson SR","year":"1943","journal-title":"Am J Orthod"},{"key":"bibr4-1055665621998534","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2008.01469.x"},{"key":"bibr5-1055665621998534","doi-asserted-by":"publisher","DOI":"10.17796\/jcpd.39.2.t623u7495h07522r"},{"key":"bibr6-1055665621998534","unstructured":"Chi AC, Damm DD, Neville BW, Allen CM, Bouquot J. 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