{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T23:49:14Z","timestamp":1778197754920,"version":"3.51.4"},"reference-count":71,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T00:00:00Z","timestamp":1655856000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>To investigate the relationship between patient-related factors (sex, cleft type, cleft extent, and Robin Sequence [RS]) and speech outcome at 5 years of age for children born with a cleft palate\u2009\u00b1\u2009 lip (CP\u2009\u00b1\u2009L).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>3157 Children (1426 female:1731 male) with a nonsyndromic CP\u2009\u00b1\u2009L, born between 2006 and 2014 in England, Wales, and Northern Ireland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>Perceptual speech analysis utilized the Cleft Audit Protocol for Speech\u2013Augmented (CAPS-A) rating and UK National Speech Outcome Standards: Speech Standard 1 (SS1)\u2014speech within the normal range, SS2a\u2014no structurally related speech difficulties or history of speech surgery, and SS3\u2014speech without significant cleft-related articulation difficulties.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>Odds of achieving SS1 were lower among boys (aOR 0.771 [CI 0.660-0.901]), those with clefts involving the lip and palate (vs palate only) (UCLP\u2014aOR 0.719 [CI 0.591-0.875]; BCLP\u2014aOR 0.360 [CI 0.279-0.463]), and clefts involving the hard palate (incomplete\u2014aOR 0.701 [CI 0.540-0.909]; complete\u2014aOR 0.393 [CI 0.308-0.501]). Similar relationships with these patient factors were observed for SS3. SS2 was affected by the extent of hard palate involvement (complete; aOR 0.449 [CI 0.348-0.580]). Although those with CP and RS were less likely to meet all 3 standards than those without RS, odds ratios were not significant when adjusting for sex and cleft extent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>Sex, cleft type, and extent of hard palate involvement have a significant impact on speech outcome at 5 years of age. Incorporating these factors into risk-adjustment models for service-level outcome reporting is recommended.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656221110094","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T01:48:45Z","timestamp":1655948925000},"page":"1578-1590","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["Investigating the Impact of Patient-Related Factors on Speech Outcomes at 5 Years of Age in Children With a Cleft Palate"],"prefix":"10.1177","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5867-2625","authenticated-orcid":false,"given":"Sophie","family":"Butterworth","sequence":"first","affiliation":[{"name":"Cleft Registry and Audit Network, Clinical Excellence Unit, The Royal College of Surgeons of England, London, 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