{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T18:19:57Z","timestamp":1788545997239,"version":"build-2803163510"},"reference-count":29,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T00:00:00Z","timestamp":1663200000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["R01DE024986"],"award-info":[{"award-number":["R01DE024986"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the sensitivity to change of daily ratings of the comfort (COMF) and behavioral\/emotional health (BEH) domains of the Infants with Clefts Observation Outcomes Instrument (iCOO) at 3 time points, and to assess the association of post-surgical interventions on iCOO ratings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>The COMF and BEH domains were completed by caregivers before (T0), immediately after (T1), and 2-months after (T2) cleft lip (CL) surgery. Analyses included descriptive statistics, correlations, t-tests, and generalized estimating equations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Caregivers ( N\u2009\u2009=\u2009\u2009140) of infants with CL with\/without cleft palate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>The COMF and BEH domain scores of the iCOO: Scale (SCALE), a summary of observable signs; and Global Impression (IMPR), a single item measuring caregivers\u2019 overall impression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Daily COMF and BEH SCALE and IMPR scores changed significantly during T1 ( P's\u2009&lt;\u20090.001) but not T0 or T2. Day 1 and 7 T0 scores were significantly higher than Day 1 and 7 T1 scores ( P's &lt;0.001 to &lt;0.012) but similar at T2 ( P's\u2009&gt;\u20090.05). After CL surgery, the combined use of immobilizers and nasal stents and the use of multiple feeding methods with treatment for gastroesophageal reflux were associated with lower daily scores in COMF and BEH SCALE and IMPR ( P's: 0.040 to &lt;0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>COMF and BEH iCOO scores were sensitive to daily changes in infant well-being following CL surgery. Future studies should further investigate impact of post-surgical treatments on infant well-being.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656221125371","type":"journal-article","created":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T03:09:00Z","timestamp":1663211340000},"page":"271-283","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Caregiver Observations of Infant Well-Being Before and After Cleft Lip Surgery"],"prefix":"10.1177","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2090-7641","authenticated-orcid":false,"given":"Janine M.","family":"Rosenberg","sequence":"first","affiliation":[{"name":"Craniofacial Center, University of Illinois Hospital and Health Sciences System, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Crilly","family":"Bellucci","sequence":"additional","affiliation":[{"name":"Shriners Hospitals for Children, Chicago Cleft\/Craniofacial, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd C.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Health Services, University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2178-7730","authenticated-orcid":false,"given":"Carrie L.","family":"Heike","sequence":"additional","affiliation":[{"name":"Seattle Children\u2019s Hospital, Craniofacial Center, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian G.","family":"Leroux","sequence":"additional","affiliation":[{"name":"University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2140-5798","authenticated-orcid":false,"given":"Salene M.","family":"Jones","sequence":"additional","affiliation":[{"name":"Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura P.","family":"Stueckle","sequence":"additional","affiliation":[{"name":"Seattle Children\u2019s Hospital, Craniofacial Center, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald L.","family":"Patrick","sequence":"additional","affiliation":[{"name":"School of Public Health, University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith","family":"Albert","sequence":"additional","affiliation":[{"name":"Shriners Hospitals for Children, Chicago Cleft\/Craniofacial, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra L.","family":"Aspinall","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital and Regional Medical Center, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen A.","family":"Kapp-Simon","sequence":"additional","affiliation":[{"name":"Shriners Hospitals for Children, Cleft\/Craniofacial Chicago, Illinois and University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,9,15]]},"reference":[{"key":"bibr1-10556656221125371","doi-asserted-by":"publisher","DOI":"10.1093\/pch\/21.5.239"},{"key":"bibr2-10556656221125371","volume-title":"The Neurobehavioral and Social-Emotional Development of Infants and Children","author":"Tronick 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