{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T10:57:52Z","timestamp":1781002672142,"version":"3.54.1"},"reference-count":32,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,11,13]],"date-time":"2022-11-13T00:00:00Z","timestamp":1668297600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      The primary goal of palatoplasty is the restoration of normal speech, that can be aimed by, among many procedures, lengthening the palate through the pushback technique; one of its complications is abnormal maxillary growth. The main factor affecting facial growth in CLP patients is believed by many to be the palatoplasty\u2014due to the large scar retraction resulting from some surgical techniques. The non-crosslinked two-layer bioabsorbable collagen matrix Mucograft\n                      <jats:sup>\u2122<\/jats:sup>\n                      (Geistlich Pharma AG, Wolhusen, Switzerland) is a potential tool to aid in wound closure in a second-intention healing situation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      The objective of this work was to test the use of an acellular dermal matrix (Mucograft\n                      <jats:sup>\u00ae<\/jats:sup>\n                      ) in an experimental model of Veau\u2013Wardill\u2013Kilner palatoplasty, as a tool to reduce scar retraction of the denuded palatine mucosa.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Twenty-four 3-week-old male Wistar rats were used. The animals were randomly divided into two groups. In the control group, an excision was made with bone exposure in the palate, simulating the defect left in the Veau\u2013Wardill\u2013Kilner palatoplasty. In the intervention group, the same procedure was performed, and the area of denuded palatine bone was treated with a bioabsorbable collagen matrix (Mucograft\n                      <jats:sup>\u00ae<\/jats:sup>\n                      ). For data collection, 9 weeks after surgery (12 weeks of life), the animals were euthanized by excessive anesthetic dosage. Maxillary growth, macroscopic appearance of the scar, pain, and bleeding were evaluated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>There were significant statistical differences between the groups for palate length growth (7.6\u2005mm\u2009+\u2009\u22120.38\u2005mm vs 5.5\u2005mm\u2009+\u2009\u22120.36\u2005mm, P\u2009=\u2009.009) and for palate width growth (1.47\u2005mm\u2009+\u2009\u22120.8\u2005mm vs \u22120.09\u2005mm\u2009+\u2009\u22120.55\u2005mm, P\u2009=\u2009.001), favoring dermal matrix group compared to controls. Whereas for pain and bleeding, there were no differences between the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>The use of dermal matrix in rats with an area of bone denudation on the palate increases maxillary length and width growth patterns. Besides, it does not increase pain, bleeding, or post-operative complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656221139674","type":"journal-article","created":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T01:24:56Z","timestamp":1668389096000},"page":"733-739","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Dermal Matrix Graft Effects on Facial Growth in a Veau\u2013Wardill\u2013Kilner Palatoplasty Model: An Experimental Study in Rats"],"prefix":"10.1177","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9283-5253","authenticated-orcid":false,"given":"Eduardo Madalosso","family":"Zanin","sequence":"first","affiliation":[{"name":"Division of Plastic Surgery, Hospital de Cl\u00ednicas de Porto Alegre, Porto Alegre, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00edcolas Endrigo","family":"Arpini","sequence":"additional","affiliation":[{"name":"Student at Universidade Federal do Rio Grande do Sul Medical School, Porto Alegre, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia Caletti","family":"Roth","sequence":"additional","affiliation":[{"name":"Student at Universidade Federal do Rio Grande do Sul Medical School, Porto Alegre, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galo Verdugo","family":"Avalos","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Hospital de Cl\u00ednicas de Porto Alegre, Porto Alegre, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele Walter","family":"Duarte","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Hospital de Cl\u00ednicas de Porto Alegre, Porto Alegre, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus Vinicius","family":"Martins Collares","sequence":"additional","affiliation":[{"name":"Head of Plastic Surgery Division, Hospital de Cl\u00ednicas de Porto Alegre, Porto Alegre, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,11,13]]},"reference":[{"key":"bibr1-10556656221139674","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23329"},{"issue":"4","key":"bibr2-10556656221139674","first-page":"619","volume":"98","author":"McWilliams BJ","year":"1996","journal-title":"Plast Reconstr Surg"},{"key":"bibr3-10556656221139674","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2009.06.001"},{"issue":"3","key":"bibr4-10556656221139674","first-page":"265","volume":"17","author":"Paniagua LM","year":"2013","journal-title":"Int Arch 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