{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:30:57Z","timestamp":1777523457538,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,1,12]],"date-time":"2023-01-12T00:00:00Z","timestamp":1673481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigates whether the use of acellular dermal matrix (ADM) affects the long-term speech outcomes in patients undergoing primary palatoplasty with radical intravelar veloplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary university-affiliated hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>A consecutive cohort of 112 patients who underwent primary palatoplasty with radical intravelar veloplasty from August 2014 to March 2018 were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>A 2\u2009\u00d7\u20092 cm-sized ADM was incorporated as an interpositional graft between the oral and nasal lining at the soft-hard palate junction. The perceptual analysis of hypernasality and articulation was performed when the age of the patient reached at least 36 months. Cleft-related characteristics and surgical factors affecting the speech outcomes were investigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The ADM was applied in 57 patients with a mean follow-up of45.76 months (SD, 10.69), while no ADM was used in 55 patients with a mean follow-up of 48.43 months (SD, 14.98). Regarding the hypernasality outcome, 33.3% (19 of 57 patients) of the ADM group and 27.3% (15 of 55 patients) of the control group showed a greater than mild-to-moderate degree. The distribution of hypernasality and articulation grade showed no significant difference between the two groups. After controlling for potential risk factors that may affect the speech outcomes, the use of ADM showed no significant relationship with velopharyngeal insufficiency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The use of ADM use in primary palatoplasty with radical intravelar veloplasty is not associated with the alteration of speech function in early childhood.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656221149519","type":"journal-article","created":{"date-parts":[[2023,1,13]],"date-time":"2023-01-13T01:34:45Z","timestamp":1673573685000},"page":"976-985","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Acellular Dermal Matrix on Long-Term Speech Outcomes in Primary Palatoplasty with Radical Intravelar Veloplasty"],"prefix":"10.1177","volume":"61","author":[{"given":"Young Chul","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5489-5178","authenticated-orcid":false,"given":"So Min","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo Ra","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8174-8915","authenticated-orcid":false,"given":"Tae Suk","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,1,12]]},"reference":[{"key":"bibr1-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.5.1.40"},{"key":"bibr2-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000001814"},{"key":"bibr3-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000218788.44591.f0"},{"key":"bibr4-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-200607000-00005"},{"key":"bibr5-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000239612.35581.c3"},{"key":"bibr6-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31817d6223"},{"key":"bibr7-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e318195ab0a"},{"key":"bibr8-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000085599.84458.D2"},{"key":"bibr9-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1597\/06-086.1"},{"key":"bibr10-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2003_040_0453_tiocto_2.0.co_2"},{"key":"bibr11-10556656221149519","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318254b2dc"},{"issue":"7","key":"bibr12-10556656221149519","volume":"31","author":"Losee 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