{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:35:31Z","timestamp":1777523731508,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T00:00:00Z","timestamp":1708473600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>\n                      <jats:italic>Objective<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>To compare hearing outcomes of early versus late tympanostomy tube insertion in patients with cleft lip and palate in a resource limited setting<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Design<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Setting<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Conducted at Queen Sirikit National Institute of Child Health, a tertiary care hospital in Bangkok, Thailand.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Patients<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>\n                      Included 76 patients under 18 with cleft anomalies undergoing tympanostomy tube insertion between January 2018 and July 2022, categorized into early (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200911) and late (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200965) tympanostomy groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Interventions<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Early tympanostomy tube placement at \u2264 3 months old, coordinated with cleft lip repair, following failed transitory evoked otoacoustic emission (TEOAE) and Type B tympanogram. Late tympanostomy tube placement preceded by a diagnosis of middle ear effusion and typically a failed TEOAE and subsequent level of testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Main Outcome Measures<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Primary outcomes: normal hearing rates and age at normal hearing. Secondary outcomes: repeated tympanostomy tube placement rate, postoperative complications, and length of hospital stays.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Results<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>\n                      Early tympanostomy tube placement was associated with higher rates of normal hearing (100% vs. 75%.\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.103) and significantly younger age at normal hearing (11 vs. 19 months,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.036). Time to normal hearing was shorter in the early group. Postoperative complications, including otorrhea, occurred more frequently in the early group, but differences were not significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Conclusion<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Early tympanostomy tube insertion improves hearing outcomes in pediatric patients with cleft lip and palate, achieving normal hearing at a significantly younger age. This approach offers a valuable alternative in resource-limited settings with constrained audiological services. Further research on long-term speech outcomes and cost-effectiveness is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656241234570","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T08:24:01Z","timestamp":1708503841000},"page":"943-949","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Hearing Outcomes in Patients with Cleft Lip and Palate in a Resource Limited Setting"],"prefix":"10.1177","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3366-2233","authenticated-orcid":false,"given":"Kanachai","family":"Boonpiraks","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Thammasat University, Khlong Luang, Pathum Thani, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanin","family":"Nawachartkosit","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Thammasat University, Khlong Luang, Pathum Thani, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nattayaporn","family":"Charunruengterakul","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Queen Sirikit National Institute of Child Health, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhave","family":"Setabutr","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Chulabhorn International College of Medicine, Thammasat University, Thammasat University Hospital, Khlong Luang, Pathum Thani, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,2,21]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jormas.2021.05.008"},{"key":"e_1_3_3_3_2","doi-asserted-by":"crossref","DOI":"10.4103\/0970-0358.57198","article-title":"Problems of middle ear and hearing in cleft children","volume":"42","author":"Sharma RK","year":"2009","unstructured":"Sharma RK, Nanda V. 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