{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T14:48:48Z","timestamp":1793803728140,"version":"4.6.1"},"reference-count":73,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate bone development in patients with alveolar clefts and permanent dentition treated with alveolar bone graft supplemented with stromal vascular fraction (SVF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Clinical, prospective, randomized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Location<\/jats:title>\n                    <jats:p>Single tertiary care institution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>Eighteen participants with unilateral alveolar cleft and permanent dentition were included. Patients with other comorbidities were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>The control group underwent alveolar bone grafting (ABG) using iliac crest bone, while the experimental group underwent the same treatment, supplemented with SVF. Adipose tissue was collected by abdominal liposuction, and the SVF was processed using mechanical methods (decantation, microfragmentation, and filtration).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measurement<\/jats:title>\n                    <jats:p>Bone formation and bone graft integration rate in alveolar cleft at 6 months postsurgery using 3-dimensional tomographic methods and density measurements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The amount of bone graft correlated with an improvement in the relationship between the cleft and noncleft sides (R\u2009=\u20090.78,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001) and an improvement in alveolar cleft density (R\u2009=\u20090.69,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.005), but did not correlate with the graft integration rate. The experimental group showed larger cleft sizes (0.83\u2009\u00d7\u20091.74\u2005cm\n                      <jats:sup>3<\/jats:sup>\n                      ,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.021) and older patients (17.35\u2009\u00d7\u200927.6 years,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.002), and did not differ in terms of bone development variables when compared to the control group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ABG supplemented with SVF showed statistically similar bone development results, but with a better trend than conventional ABG. Additionally, the studied groups had asymmetric pre-existing characteristics, with greater severity in the experimental group. A larger study will be necessary to mitigate preoperative characteristic differences and to more accurately compare the results between the methods.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656241296711","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T05:42:04Z","timestamp":1732513324000},"page":"133-143","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Alveolar Bone Graft Supplemented With Stromal Vascular Fraction in Patients With Permanent Dentition: A Randomized Study"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2677-4018","authenticated-orcid":false,"given":"Kleber Tetsuo","family":"Kurimori","sequence":"first","affiliation":[{"name":"S\u00e3o Paulo University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Endrigo Oliveira","family":"Bastos","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Roberto Pelucio","family":"Camara","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9196-5550","authenticated-orcid":false,"given":"Beatriz","family":"Mascarenhas Dias","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2291-7381","authenticated-orcid":false,"given":"Giovanna Layse","family":"Uyeda","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivaldo","family":"Alonso","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,11,25]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-63290-2"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000002778"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2000_037_0229_moacbg_2.3.co_2"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jobcr.2013.02.002"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2003.08.023"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000003345"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000004125"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1597\/14-290"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/10556656211007692"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tec.2009.0824"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31825c75ba"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.06.670"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2018.03.009"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000293870.64781.12"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2012.08.015"},{"key":"e_1_3_2_17_2","first-page":"767","volume-title":"Plastic and Reconstructive Surgery","author":"Liang F","year":"2017","unstructured":"Liang F, Yen SLK, Imahiyerobo T, et al. 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