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Cranial and plastic surgeries were performed to correct hypertelorism and improve the esthetic appearance of the frontonasal region. In the permanent dentition, the patient presented a Class II, division 1 malocclusion with severe maxillary constriction and bilateral posterior crossbite. Comprehensive orthodontic treatment started at 12 years of age and included rapid maxillary expansion followed by fixed appliance. Orthognathic surgery was performed at 21 years of age involving a forward movement of both maxilla and mandible. After debonding, veneers were made in maxillary anterior teeth to improve tooth shape and Bolton discrepancies. An improvement in facial esthetics and an adequate final occlusion were achieved. Multidisciplinary treatment was essential for morphological rehabilitation and social inclusion in patients with rare craniofacial anomalies.<\/jats:p>","DOI":"10.1177\/10556656241307738","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T05:56:15Z","timestamp":1736402175000},"page":"860-867","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Multidisciplinary Oral Rehabilitation of Complex Frontonasal Dysplasia: A Case Report"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5880-3960","authenticated-orcid":false,"given":"Roberta Costa e","family":"Silva","sequence":"first","affiliation":[{"name":"Department of Orthodontics, Bauru Dental School, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiano","family":"Tonello","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Carlos da Cunha","family":"Bastos","sequence":"additional","affiliation":[{"name":"Division of Maxillofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina Magrini Guedes de","family":"Azevedo","sequence":"additional","affiliation":[{"name":"Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roseli Maria","family":"Zechi-Ceide","sequence":"additional","affiliation":[{"name":"Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Garib","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Bauru Dental School, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4015-0623","authenticated-orcid":false,"given":"Felicia","family":"Miranda","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Bauru Dental School, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz Martins","family":"de Andrade","sequence":"additional","affiliation":[{"name":"Privade Practice, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Fernando Castanha","family":"Henriques","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Bauru Dental School, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano Porto","family":"Peixoto","sequence":"additional","affiliation":[{"name":"Division of Orthodontics, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,1,9]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.4103\/0976-3147.91947"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(70)80374-2"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(88)90014-X"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.7181\/acfs.2019.00570"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0901-5027(96)80048-8"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0503(76)80013-6"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.63319"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(96)90403-0"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1597\/15-286"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-017-0274-z"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2013.06.001"},{"key":"e_1_3_2_13_2","first-page":"269","article-title":"Influence of respiratory pattern on craniofacial growth","volume":"51","author":"McNamara JA","year":"1981","unstructured":"McNamara JA. 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